A Systematic Review of In Vitro Activity of Medicinal Plants from Sub-Saharan Africa against Campylobacter spp.
Joint Authors
Sigauque, Betuel
Hlashwayo, Delfina Fernandes
Barbosa, Filomena
Langa, Sílvia
Bila, Custódio Gabriel
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-13, 13 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-05-15
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Introduction.
Campylobacter spp.
are zoonotic bacteria that cause gastroenteritis in humans and may cause extraintestinal infections such as Guillain-Barré syndrome, reactive arthritis, and bacteremia.
Resistance to antibiotics is an increasing concern in the Sub-Saharan Africa; thus, search for alternatives such as plant-based active ingredients is important in order to develop new drugs.
Objectives.
To present a systematic review of in vitro and in vivo studies of the antibacterial activity of medicinal plants from Sub-Saharan Africa against Campylobacter spp.
Methodology.
Studies published until March 2020 on medicinal plants used against Campylobacter spp.
from each country of Sub-Saharan Africa were searched on PubMed, Science Direct, AJOL, and Google Scholar.
Articles were selected based on the existence of information regarding in vitro and in vivo activity of medicinal plants against Campylobacter spp.
Results.
A total of 47 medicinal plants belonging to 28 families were studied for in vitro activity against Campylobacter spp.
No plant was studied in vivo.
Plants from Fabaceae family were the most commonly studied.
The plants with the strongest antimicrobial activities were Cryptolepis sanguinolenta and Terminalia macroptera.
The root extracts from these plants were effective, and both had a minimal inhibitory concentration (MIC) of 25 μg/ml.
Seven pure compounds were isolated and analyzed for activity against Campylobacter spp.
The compound cryptolepine from C.
sanguinolenta was the most effective with MIC values ranging between 6.25 and 25 μg/ml.
Conclusion.
Several native plants from the Sub-Saharan Africa region were studied for in vitro activity against Campylobacter spp.
Some plants seemed very effective against the bacteria.
Chemical compounds from three plants have been isolated and analyzed, but further studies are needed in order to produce new and effective drugs.
American Psychological Association (APA)
Hlashwayo, Delfina Fernandes& Barbosa, Filomena& Langa, Sílvia& Sigauque, Betuel& Bila, Custódio Gabriel. 2020. A Systematic Review of In Vitro Activity of Medicinal Plants from Sub-Saharan Africa against Campylobacter spp.. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1158531
Modern Language Association (MLA)
Hlashwayo, Delfina Fernandes…[et al.]. A Systematic Review of In Vitro Activity of Medicinal Plants from Sub-Saharan Africa against Campylobacter spp.. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-13.
https://search.emarefa.net/detail/BIM-1158531
American Medical Association (AMA)
Hlashwayo, Delfina Fernandes& Barbosa, Filomena& Langa, Sílvia& Sigauque, Betuel& Bila, Custódio Gabriel. A Systematic Review of In Vitro Activity of Medicinal Plants from Sub-Saharan Africa against Campylobacter spp.. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-13.
https://search.emarefa.net/detail/BIM-1158531
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158531