![](/images/graphics-bg.png)
PHEMA Hydrogels Obtained by Infrared Radiation for Cartilage Tissue Engineering
Joint Authors
Passos, Marcele F.
Carvalho, Nayara M. S.
Jardini, André L.
Bavaresco, V. P.
Wolf Maciel, Maria Regina
Rodrigues, A. A.
Maciel Filho, Rubens
Source
International Journal of Chemical Engineering
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-01-31
Country of Publication
Egypt
No. of Pages
9
Abstract EN
Although the exposure of polymeric materials to radiation is a well-established process, little is known about the relationship between structure and property and the biological behavior of biomaterials obtained by thermal phenomena at 1070 nm wavelength.
This study includes results concerning the use of a novel infrared radiation source (ytterbium laser fiber) for the synthesis of poly(2-hydroxyethyl methacrylate) (PHEMA) hydrogel in order to produce medical devices.
The materials were obtained by means of free radical polymerization mechanism and evaluated regarding its cross-linking degree, polymer chain mobility, thermal, and mechanical properties.
Their potential use as a biomaterial toward cartilage tissue was investigated through incubation with chondrocytes cells culture by dimethylmethylene blue (DMMB) dye and DNA quantification.
Differential scanning calorimetry (DSC) results showed that glass transition temperature (Tg) was in the range 103°C–119°C, the maximum degree of swelling was 70.8%, and indentation fluency test presented a strain of 56%–85%.
A significant increase of glycosaminoglycans (GAGs) concentration and DNA content in cells cultured with 40 wt% 2-hydroxyethyl methacrylate was observed.
Our results showed the suitability of infrared laser fiber in the free radicals formation and in the rapid polymer chain growth, and further cross-linking.
The porous material obtained showed improvements concerning cartilage tissue regeneration.
American Psychological Association (APA)
Passos, Marcele F.& Carvalho, Nayara M. S.& Rodrigues, A. A.& Bavaresco, V. P.& Jardini, André L.& Wolf Maciel, Maria Regina…[et al.]. 2019. PHEMA Hydrogels Obtained by Infrared Radiation for Cartilage Tissue Engineering. International Journal of Chemical Engineering،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1158654
Modern Language Association (MLA)
Passos, Marcele F.…[et al.]. PHEMA Hydrogels Obtained by Infrared Radiation for Cartilage Tissue Engineering. International Journal of Chemical Engineering No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1158654
American Medical Association (AMA)
Passos, Marcele F.& Carvalho, Nayara M. S.& Rodrigues, A. A.& Bavaresco, V. P.& Jardini, André L.& Wolf Maciel, Maria Regina…[et al.]. PHEMA Hydrogels Obtained by Infrared Radiation for Cartilage Tissue Engineering. International Journal of Chemical Engineering. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1158654
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158654