Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity
Joint Authors
Source
Evidence-Based Complementary and Alternative Medicine
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-06-11
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
As the leading cause of cancer-related death, hepatocellular carcinoma (HCC) threatens human health and limited treatments are available to cure the disease efficiently and effectively.
The particularly immunotolerant environment of the liver lowers the efficacy of current therapies in patients with advanced HCC.
Traditional Chinese medicine (TCM) is gathering increasing interest due to the immunoregulatory properties of certain compounds.
In advanced HCC, TCM can restore immunosurveillance to promote antitumor effects in several ways, including the upregulation of immunostimulatory factors and the downregulation of immunosuppressive factors.
The characteristic multitarget regulation of TCM compounds may provide new insights regarding effective HCC immunotherapies.
Here, we review the immunoregulatory potency of TCMs for treating HCC and explain how individual TCM drugs and complex formulas remodel the immune environment in various cell- and cytokine-dependent manners.
American Psychological Association (APA)
Jia, Wentao& Wang, Lina. 2020. Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1158773
Modern Language Association (MLA)
Jia, Wentao& Wang, Lina. Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1158773
American Medical Association (AMA)
Jia, Wentao& Wang, Lina. Using Traditional Chinese Medicine to Treat Hepatocellular Carcinoma by Targeting Tumor Immunity. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1158773
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1158773