Sustained-Release Fillers for Dentin Disinfection: An Ex Vivo Study

Joint Authors

Kirmayer, David
Friedman, Michael
Steinberg, Doron
Funk, Bernhard
Sahar-Helft, Sharonit

Source

International Journal of Dentistry

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-05-22

Country of Publication

Egypt

No. of Pages

9

Main Subjects

Dental

Abstract EN

Enterococcus faecalis is the most commonly recovered species from failed root canal treatments.

In this study, we tested the capability of a novel intracanal sustained-release filler (SRF) containing cetylpyridinium chloride (CPC) to disinfect dentinal tubules of segmented human tooth specimens.

Human dental root specimens were infected with E.

faecalis V583 for 3 weeks in a static environment.

The tested intracanal medicaments were SRF-CPC and calcium hydroxide (CH).

Each medicament was introduced into the canal of the dental specimen and incubated for 7 days.

The bacteriological samples were taken by shaving the dentine surrounding the root canal with dental burs ranging in size from ISO 014-020.

The obtained dentine powder was collected in test tubes containing phosphate-buffered saline, sonicated, and plated on agar plates.

Colony-forming units were counted after 48 h of incubation.

Random specimens were also examined under confocal laser scanning microscopy and scanning electron microscopy.

A statistical difference was found in the bacterial counts obtained from all layers of infected dentin between the control and the SRF-CPC groups.

CH reduced bacterial viability significantly only in the first layer of the infected dentin, up to 150 μm into the dentinal tubules.

CLSM images showed that SRF-CPC killed most bacteria throughout the infected dentin up to 700 μm of penetration.

SEM images demonstrated the adhesion ability of SRF-CPC to the dentinal wall.

In conclusion, SRF-CPC is a potential intracanal medicament for disinfecting dentinal tubules.

American Psychological Association (APA)

Funk, Bernhard& Sahar-Helft, Sharonit& Kirmayer, David& Friedman, Michael& Steinberg, Doron. 2019. Sustained-Release Fillers for Dentin Disinfection: An Ex Vivo Study. International Journal of Dentistry،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1158916

Modern Language Association (MLA)

Funk, Bernhard…[et al.]. Sustained-Release Fillers for Dentin Disinfection: An Ex Vivo Study. International Journal of Dentistry No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1158916

American Medical Association (AMA)

Funk, Bernhard& Sahar-Helft, Sharonit& Kirmayer, David& Friedman, Michael& Steinberg, Doron. Sustained-Release Fillers for Dentin Disinfection: An Ex Vivo Study. International Journal of Dentistry. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1158916

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1158916