Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials
Joint Authors
Liu, Rong
Cao, Zanfeng
Yang, Zhanzheng
Liang, Zijing
Cen, Qingyan
Zhang, Zuopeng
Liang, Hengrui
Zeng, Liangbo
Xie, Yubao
Wang, Youping
Source
Emergency Medicine International
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-04
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The purpose of this meta-analysis was to compare the efficacy and safety of prone versus supine position ventilation for adult acute respiratory distress syndrome (ARDS) patients.
The electronic databases of PubMed, Embase, and the Cochrane Library were systematically searched from their inception up to September 2020.
The relative risks (RRs) and weighted mean differences (WMDs) with corresponding 95% confidence intervals (CIs) were employed to calculate pooled outcomes using the random-effects models.
Twelve randomized controlled trials that had recruited a total of 2264 adults with ARDS were selected for the final meta-analysis.
The risk of mortality in patients who received prone position ventilation was 13% lower than for those who received supine ventilation, but this effect was not statistically significant (RR: 0.87; 95% CI: 0.75–1.00; P = 0.055).
There were no significant differences between prone and supine position ventilation on the duration of mechanical ventilation (WMD: −0.22; P = 0.883) or ICU stays (WMD: –0.39; P = 0.738).
The pooled RRs indicate that patients who received prone position ventilation had increased incidence of pressure scores (RR: 1.23; P = 0.003), displacement of a thoracotomy tube (RR: 3.14; P = 0.047), and endotracheal tube obstruction (RR: 2.45; P = 0.001).
The results indicated that prone positioning during ventilation might have a beneficial effect on mortality, though incidence of several adverse events was significantly increased for these patients.
American Psychological Association (APA)
Cao, Zanfeng& Yang, Zhanzheng& Liang, Zijing& Cen, Qingyan& Zhang, Zuopeng& Liang, Hengrui…[et al.]. 2020. Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials. Emergency Medicine International،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1159038
Modern Language Association (MLA)
Cao, Zanfeng…[et al.]. Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials. Emergency Medicine International No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1159038
American Medical Association (AMA)
Cao, Zanfeng& Yang, Zhanzheng& Liang, Zijing& Cen, Qingyan& Zhang, Zuopeng& Liang, Hengrui…[et al.]. Prone versus Supine Position Ventilation in Adult Patients with Acute Respiratory Distress Syndrome: A Meta-Analysis of Randomized Controlled Trials. Emergency Medicine International. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1159038
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159038