Erythromycin for Promoting the Postpyloric Placement of Feeding Tubes: A Systematic Review and Meta-Analysis

Joint Authors

Jiang, Qing-Jun
Jiang, Cai-Feng
Chen, Qi-Tong
Shi, Jian
Shi, Bin

Source

Gastroenterology Research and Practice

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-04-03

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Diseases

Abstract EN

Background.

Critically ill patients can benefit from enteral nutrition with postpyloric feeding tubes, but the low success rate limits its wide use.

Erythromycin could elevate the success rate of tube insertion, but its clinical efficiency still remains controversial.

Methods.

Included studies must be RCTs which assessed the success rate of postpyloric feeding tube insertion using erythromycin.

Results.

284 patients were enrolled in six studies.

Meta-analysis showed that erythromycin significantly increases the rate of successful postpyloric feeding tube placement (RR 1.45, 95% CI (1.12, 1.86)) and did not increase the risk of adverse effects (RR 2.15, 95% CI (0.20, 22.82)).

Subgroup analysis showed that unweighted feeding tubes (RR 1.47, 95% CI (1.03, 2.11)) could significantly increase the success rate.

Country of study, intravenous route of erythromycin, and year of participant enrollment did not influence these results.

Conclusions.

Erythromycin significantly increases the success rate of postpyloric feeding tube placement.

This suggests that erythromycin can be used as an auxiliary method to improve the success rate of bedside insertion.

American Psychological Association (APA)

Jiang, Qing-Jun& Jiang, Cai-Feng& Chen, Qi-Tong& Shi, Jian& Shi, Bin. 2018. Erythromycin for Promoting the Postpyloric Placement of Feeding Tubes: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159254

Modern Language Association (MLA)

Jiang, Qing-Jun…[et al.]. Erythromycin for Promoting the Postpyloric Placement of Feeding Tubes: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1159254

American Medical Association (AMA)

Jiang, Qing-Jun& Jiang, Cai-Feng& Chen, Qi-Tong& Shi, Jian& Shi, Bin. Erythromycin for Promoting the Postpyloric Placement of Feeding Tubes: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159254

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1159254