Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency

Joint Authors

Ben-Skowronek, Iwona
Wójcik, Dorota
Szalewski, Leszek
Pietryka-Michałowska, Elżbieta
Borowicz, Janusz
Pels, Elżbieta

Source

International Journal of Endocrinology

Issue

Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2019-01-21

Country of Publication

Egypt

No. of Pages

8

Main Subjects

Biology

Abstract EN

Vitamin D deficiency is a common risk factor for multifactorial diseases, and it seems to be associated with growth hormone deficiency (GHD).

Vitamin D could prevent dental caries.

The goal of this study was to identify whether there is an association between hormonal therapy with growth hormone (GH), vitamin D3 supplementation, vitamin D3 levels, and the occurrence of caries among children affected by GHD.

The study group consisted of patients from the Department of Endocrinology and Diabetology of the University Paediatric Hospital at the Medical University of Lublin treated with recombinant human GH for pituitary GHD.

It was conducted between October 2014 and June 2015.

The study group included 121 children and adolescents aged 6 to 18 years, with 56 children from rural areas and 65 from urban areas.

The study group was stratified by the area of residence.

We found the statistically significant impact of vitamin D3 concentration on the average value of the DMFT (decayed, missed, and filled teeth) index and its component—DT (decayed teeth), which was noted in subjects from rural areas.

Among patients from urban areas, we found a statistically significant correlation between duration of therapy and the DMFT index.

An increase in duration of GH therapy by 10 months leads to a mean increase in DMFT index by 0.70.

Based on multiple regression analysis, we developed the following model: value of DT = 3.10 − 0.73∗category of vitamin D3 concentration − 0.07∗duration of supplementation (in months).

In this model, variables with a significant impact on the value of DT in the group of patients from rural areas include time of vitamin D3 supplementation and category of vitamin D3 concentration.

Greater emphasis should be placed on promoting vitamin D3 as a potentially effective agent reducing the number of dental caries, especially among patients with GHD.

American Psychological Association (APA)

Wójcik, Dorota& Szalewski, Leszek& Pietryka-Michałowska, Elżbieta& Borowicz, Janusz& Pels, Elżbieta& Ben-Skowronek, Iwona. 2019. Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1159372

Modern Language Association (MLA)

Wójcik, Dorota…[et al.]. Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency. International Journal of Endocrinology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1159372

American Medical Association (AMA)

Wójcik, Dorota& Szalewski, Leszek& Pietryka-Michałowska, Elżbieta& Borowicz, Janusz& Pels, Elżbieta& Ben-Skowronek, Iwona. Vitamin D3 and Dental Caries in Children with Growth Hormone Deficiency. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1159372

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1159372