Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis
Joint Authors
Su, Shan-shan
Sun, Ning-ning
Yang, Yu-xin
Liang, Yufei
Zheng, Guoqi
Yin, Wenjie
Song, Hui
Liu, Ying-ying
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-15
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
To determine effects of the biochemical and cytological properties of blood, serum, and ascites on survival of patients with malignant peritoneal effusion (MPeE), including malignant peritoneal mesothelioma (MPeM) and peritoneal carcinomatosis (PC), we conducted a retrospective study of patients with MPeE and healthy controls.
Potential prognostic factors were identified as follows: age, sex, blood neutrophil-to-lymphocyte ratio (NLR), serum parameters, ascites parameters, serum-ascites albumin gradient, and the ascites-serum LDH ratio.
Compared to those of the control group, serum albumin levels were significantly lower, and the NLR and serum LDH levels were significantly higher in the MPeE group.
Overall survival (OS) was longer in patients with MPeM compared to that in patients with PC.
Compared with patients in the MPeM, patients with PC had higher NLRs, ascites glucose levels, serum-ascites albumin gradients, and serum LDH levels.
In contrast, their ascites albumin levels and ascites-serum LDH ratios were lower.
Univariate analyses indicated that the NLR, serum LDH levels, ascites LDH levels, ascites coenocyte levels, and the ascites coenocyte-to-monocyte ratios affected the OS.
Multivariate analyses identified only serum and ascites LDH levels as independent prognostic factors.
American Psychological Association (APA)
Su, Shan-shan& Zheng, Guoqi& Yin, Wenjie& Liang, Yufei& Liu, Ying-ying& Song, Hui…[et al.]. 2018. Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159398
Modern Language Association (MLA)
Su, Shan-shan…[et al.]. Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis. Gastroenterology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1159398
American Medical Association (AMA)
Su, Shan-shan& Zheng, Guoqi& Yin, Wenjie& Liang, Yufei& Liu, Ying-ying& Song, Hui…[et al.]. Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159398
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159398