Efficacy and Safety of Argon Plasma Coagulation for Hemorrhagic Chronic Radiation Proctopathy: A Systematic Review
Joint Authors
Feng, Jue-Rong
Wang, Fan
Liu, Jing
Peng, Yanan
Wang, Haizhou
Fang, Shilin
Zhang, Meng
Chang, Ying
Shi, Xianyan
Zhao, Qiu
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-25
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Hemorrhagic chronic radiation proctopathy (CRP) is a common complication after pelvic radiotherapy in patients with prostate or gynecological cancers.
This systematic review was conducted to evaluate the efficacy and safety of argon plasma coagulation (APC) in treating hemorrhagic CRP.
The databases of PubMed, Embase, and Cochrane Library were searched for related studies from inception to July 2017.
Finally, 33 studies were identified with a total of 821 hemorrhagic CRP patients.
After APC treatment, hemoglobin levels increased from 7.7–13.4 g/L to 11–14 g/L (including 15 studies).
All (n=33) studies reported an effective rate in rectal bleeding, among which five studies had a rate of 100%.
Short-term complications were reported in 31 studies, while long-term complications in 33 studies and no complication in 11 studies.
As for the severe complications, perforation was reported by 2 out of 33 studies, and the incidences were 3.3% (1/30) and 3.7% (1/27), respectively.
As for APC setting, argon gas flow rate (median 1.5 L/min) and electric power (median 50 W) had no significant influence on complications and hemostasis.
In conclusion, current literature indicated that APC therapy was an effective and safe strategy for hemorrhagic CRP, and large-scale prospective studies are needed to warrant our study.
American Psychological Association (APA)
Peng, Yanan& Wang, Haizhou& Feng, Jue-Rong& Fang, Shilin& Zhang, Meng& Wang, Fan…[et al.]. 2018. Efficacy and Safety of Argon Plasma Coagulation for Hemorrhagic Chronic Radiation Proctopathy: A Systematic Review. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1159491
Modern Language Association (MLA)
Peng, Yanan…[et al.]. Efficacy and Safety of Argon Plasma Coagulation for Hemorrhagic Chronic Radiation Proctopathy: A Systematic Review. Gastroenterology Research and Practice No. 2018 (2018), pp.1-14.
https://search.emarefa.net/detail/BIM-1159491
American Medical Association (AMA)
Peng, Yanan& Wang, Haizhou& Feng, Jue-Rong& Fang, Shilin& Zhang, Meng& Wang, Fan…[et al.]. Efficacy and Safety of Argon Plasma Coagulation for Hemorrhagic Chronic Radiation Proctopathy: A Systematic Review. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-14.
https://search.emarefa.net/detail/BIM-1159491
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159491