Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study
Joint Authors
Pes, Gianni
Bibbò, Stefano
Manetti, Roberto
Rojas, Rodrigo
Fozza, Claudio
Dore, Maria Pina
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-23
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Introduction.
Coeliac disease (CD) and immune thrombocytopenic purpura (ITP) are immune conditions, often associated with other immune disorders.
In recent years, increasing attention has been directed towards the association between ITP and CD.
Aim.
To investigate the frequency of ITP in CD patients and vice versa and to assess the risk of their association.
Patients and Methods.
This was a prospective observational study.
All consecutive patients with CD or ITP attending our department were enrolled between January 2016 and December 2017.
All patients with CD were screened for ITP and patients with ITP for CD.
Odds ratios (ORs) were calculated based on the prevalence in the general population.
Results.
Two hundred sixty-one CD patients (212 female, mean age 47 ± 16.1 years) and 32 ITP patients (17 female, mean age 57.8 ± 17.4 years) were enrolled.
In the CD cohort, two patients (2/261; 0.8%) reported a previous diagnosis of ITP, compared to the general population; OR was 15.3 (95% CI, 3.82–61.73; p<0.0001).
Similarly, in the ITP cohort, two patients (2/32; 6.3%) had a previous diagnosis of CD (OR: 9.89, 95% CI, 2.27–43.16; p=0.0002).
Discussion.
A greater frequency of ITP in coeliac patients and vice versa was observed in our study, suggesting an increased risk for patients of developing both disorders.
American Psychological Association (APA)
Bibbò, Stefano& Fozza, Claudio& Pes, Gianni& Rojas, Rodrigo& Manetti, Roberto& Dore, Maria Pina. 2018. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1159641
Modern Language Association (MLA)
Bibbò, Stefano…[et al.]. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1159641
American Medical Association (AMA)
Bibbò, Stefano& Fozza, Claudio& Pes, Gianni& Rojas, Rodrigo& Manetti, Roberto& Dore, Maria Pina. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1159641
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159641