Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study

Joint Authors

Pes, Gianni
Bibbò, Stefano
Manetti, Roberto
Rojas, Rodrigo
Fozza, Claudio
Dore, Maria Pina

Source

Gastroenterology Research and Practice

Issue

Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-4, 4 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2018-04-23

Country of Publication

Egypt

No. of Pages

4

Main Subjects

Diseases

Abstract EN

Introduction.

Coeliac disease (CD) and immune thrombocytopenic purpura (ITP) are immune conditions, often associated with other immune disorders.

In recent years, increasing attention has been directed towards the association between ITP and CD.

Aim.

To investigate the frequency of ITP in CD patients and vice versa and to assess the risk of their association.

Patients and Methods.

This was a prospective observational study.

All consecutive patients with CD or ITP attending our department were enrolled between January 2016 and December 2017.

All patients with CD were screened for ITP and patients with ITP for CD.

Odds ratios (ORs) were calculated based on the prevalence in the general population.

Results.

Two hundred sixty-one CD patients (212 female, mean age 47 ± 16.1 years) and 32 ITP patients (17 female, mean age 57.8 ± 17.4 years) were enrolled.

In the CD cohort, two patients (2/261; 0.8%) reported a previous diagnosis of ITP, compared to the general population; OR was 15.3 (95% CI, 3.82–61.73; p<0.0001).

Similarly, in the ITP cohort, two patients (2/32; 6.3%) had a previous diagnosis of CD (OR: 9.89, 95% CI, 2.27–43.16; p=0.0002).

Discussion.

A greater frequency of ITP in coeliac patients and vice versa was observed in our study, suggesting an increased risk for patients of developing both disorders.

American Psychological Association (APA)

Bibbò, Stefano& Fozza, Claudio& Pes, Gianni& Rojas, Rodrigo& Manetti, Roberto& Dore, Maria Pina. 2018. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1159641

Modern Language Association (MLA)

Bibbò, Stefano…[et al.]. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1159641

American Medical Association (AMA)

Bibbò, Stefano& Fozza, Claudio& Pes, Gianni& Rojas, Rodrigo& Manetti, Roberto& Dore, Maria Pina. Increased Frequency of Immune Thrombocytopenic Purpura in Coeliac Disease and Vice Versa: A Prospective Observational Study. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1159641

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1159641