The Comparison between Endoscopic Submucosal Dissection and Surgery in Gastric Cancer: A Systematic Review and Meta-Analysis
Joint Authors
Ren, Mudan
Lu, Guifang
He, Shuixiang
Hu, Junbi
Li, Yarui
Lu, Xinlan
Zhang, Dan
Chu, Dake
Zhao, Yan
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-02-18
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Aims.
There are two treatment modalities for early gastric cancer (EGC)—surgery and endoscopic submucosal dissection (ESD).
We aimed to compare the safety and efficacy of ESD with surgery.
Method.
The article was performed by searching PubMed databases.
Data were extracted using predefined form and odds ratios (OR) with 95% confidence intervals (CI) calculated and P value.
Results.
13 studies were identified.
The incidence of perforation in two groups was different [OR = 6.18 (95% CI: 1.37–27.98), P=0.02].
The prevalences of synchronous and metachronous cancer in the ESD group were higher than those in the surgery group [OR = 8.52 (95% CI: 1.99–36.56), P = 0.004 and OR = 7.15 (95% CI: 2.95–17.32), P<0.0001].
The recurrence and complete resection rates were different [OR = 6.93 (95% CI: 2.83–16.96), P<0.0001 and OR = 0.32 (95% CI: 0.20–0.52), P<0.00001].
Compared with the surgery group, the hospital stay was shorter [IV = −7.15 (95% CI: −9.08–5.22), P<0.00001], the adverse event rate was lower, and the quality of life (QOL) was better in the ESD group.
The difference of bleeding was not found.
Conclusion.
ESD appears to be preferable for EGC, due to a lower rate of adverse events, shorter hospital stay, cheaper cost, and higher QOL.
American Psychological Association (APA)
Hu, Junbi& Zhao, Yan& Ren, Mudan& Li, Yarui& Lu, Xinlan& Lu, Guifang…[et al.]. 2018. The Comparison between Endoscopic Submucosal Dissection and Surgery in Gastric Cancer: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159706
Modern Language Association (MLA)
Hu, Junbi…[et al.]. The Comparison between Endoscopic Submucosal Dissection and Surgery in Gastric Cancer: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1159706
American Medical Association (AMA)
Hu, Junbi& Zhao, Yan& Ren, Mudan& Li, Yarui& Lu, Xinlan& Lu, Guifang…[et al.]. The Comparison between Endoscopic Submucosal Dissection and Surgery in Gastric Cancer: A Systematic Review and Meta-Analysis. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159706
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159706