![](/images/graphics-bg.png)
Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer?
Joint Authors
Wang, Zhen-ning
Xu, Hui-mian
Zhang, Jia-Le
Zhu, Zhi
Huang, Bao-Jun
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-01
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Aim.
Gastrectomy with lymph node dissection is standard treatment in gastric cancer.
This study aimed to explore whether preoperative investigation finds could predict lymph node metastatic scope in gastric carcinoma so that the optimal surgical procedure could be selected.
Materials and Methods.
Radical gastrectomy patients (n=378) were separated into two groups according to the lymph node metastatic scope.
Univariate and multivariate analyses of preoperative examination results were performed to identify the predictors of metastatic scope.
ROC curves were constructed, and the area under the curve (AUC) was calculated to estimate diagnostic values.
Results.
Serum CEA (OR: 3.73; 95% CI: 1.84–7.56; P≤0.001), tumor size (OR: 2.07; 95% CI: 1.08–3.98; P=0.03), and CT examination results (OR: 17.81; 95% CI: 9.18–34.55; P≤0.001) were identified as independent predictors.
The AUC proved that they possessed significant diagnostic value.
When CT examination was negative, the combination of serum CEA and tumor size showed high specificity (95.3%; 164/172), negative predictive value (92.7%; 164/177), and accuracy (89.0%; 170/191).
Conclusions.
Preoperative serum CEA, tumor size, and CT examination are independent predictors of lymph node metastatic scope and can be used for selecting the appropriate lymphadenectomy pattern in gastric cancer patients.
American Psychological Association (APA)
Zhang, Jia-Le& Wang, Zhen-ning& Xu, Hui-mian& Zhu, Zhi& Huang, Bao-Jun. 2018. Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer?. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159750
Modern Language Association (MLA)
Zhang, Jia-Le…[et al.]. Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer?. Gastroenterology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1159750
American Medical Association (AMA)
Zhang, Jia-Le& Wang, Zhen-ning& Xu, Hui-mian& Zhu, Zhi& Huang, Bao-Jun. Can Preoperative Examination Help Choose the Best Surgical Procedure in Gastric Cancer?. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1159750
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1159750