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Ultrasound Microvascular Blood Flow Evaluation: A New Tool for the Management of Thyroid Nodule?
Joint Authors
Casella, Claudio
Cappelli, Carlo
Pirola, Ilenia
Gandossi, Elena
Castellano, Maurizio
Cristiano, Alessandra
Marini, Fiorella
Lombardi, Davide
Agosti, Barbara
Ferlin, Alberto
Source
International Journal of Endocrinology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-03-25
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Background.
Toshiba Medical System has developed a new Doppler technique [Superb Microvascular Imaging (SMI)] that has improved microvascular flow imaging.
SMI depicts perinodular and intranodular thyroid microvascular flow in higher detail compared to standard colour Doppler (CD) and power Doppler (PD) imaging.
Objective.
Assess the nodular microvascular architecture by SMI compared to CD and PD features in a series of thyroid nodules submitted to fine needle aspiration cytology, in order to evaluate the potential of SMI in detecting thyroid cancer.
Materials and Methods.
From April 2016 to July 2017, 254 patients with thyroid nodules, evaluated as at high risk for malignancy in agreement with AACE/ACE/AME guidelines, were submitted to cytology.
All nodules were previously submitted to ultrasound grayscale, CD, PD, and SMI evaluation.
Benign and malignant nodules were stratified in accordance to the number of vessels visualised by SMI: score 1 with a maximum of two blood vessels and score 2 with three or more vessels.
Results.
Score 1 was found in 59.6% of benign nodules and in 17.9% of malignant nodules, whereas score 2 was found in 40.4% and in 82.1%, respectively (sensitivity 81.7%; specificity 60.5%, p<0.001).
Variables significantly associated with malignancy in the univariate analysis were gender (OR, 0.18; 95% CI, 0.08-0.37; p<0.001), vascularity (OR, 1.91; 95% CI, 1.65-3.89; p<0.001), and SMI (OR, 6.72; 95% CI, 3.89-11.59; p<0.001); multivariate logistic model confirmed SMI score 2 as an independent risk factor for malignancy (OR, 6.99; 95% CI, 3.46-12.09; p<0.001).
Conclusions.
This prospective pilot study showed that SMI can depict intranodular flow in higher detail compared to CDI and PDI, thus improving thyroid cancer detection.
American Psychological Association (APA)
Cappelli, Carlo& Pirola, Ilenia& Gandossi, Elena& Marini, Fiorella& Cristiano, Alessandra& Casella, Claudio…[et al.]. 2019. Ultrasound Microvascular Blood Flow Evaluation: A New Tool for the Management of Thyroid Nodule?. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1160057
Modern Language Association (MLA)
Cappelli, Carlo…[et al.]. Ultrasound Microvascular Blood Flow Evaluation: A New Tool for the Management of Thyroid Nodule?. International Journal of Endocrinology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1160057
American Medical Association (AMA)
Cappelli, Carlo& Pirola, Ilenia& Gandossi, Elena& Marini, Fiorella& Cristiano, Alessandra& Casella, Claudio…[et al.]. Ultrasound Microvascular Blood Flow Evaluation: A New Tool for the Management of Thyroid Nodule?. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1160057
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1160057