Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer
Joint Authors
Arihiro, Koji
Chayama, Kazuaki
Serikawa, Masahiro
Ishii, Yasutaka
Tsushima, Ken
Murakami, Yoshiaki
Itsuki, Hiroshi
Sasaki, Tamito
Furukawa, Yoshinari
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-04-18
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Aim.
We examined the effectiveness of bile juice cytology for distinguishing between benign and malignant gallbladder lesions of the protruding type with various sampling points, sampling methods, and macroscopic forms in order to discuss the effectiveness of the endoscopic transpapillary gallbladder drainage (ETGD) cytology.
Methods.
We studied 162 cases of patients with a lesion localized within the gallbladder.
At first, we examined the effectiveness for diagnosis of ETBD cytology using ERC and then that of the first ETGD cytology after placing the ETGD.
Next, we examined the diagnostic effectiveness of the washed ETGD cytology by using the ETGD.
Finally, we examined complications.
Results.
In the final diagnoses, we identified 33 cases of adenocarcinoma, 10 cases of adenoma, 63 cases of ADM, 35 cases of nonneoplastic polyp, and 21 cases of chronic cholecystitis.
It was found that the sensitivity of ETBD cytology was 3.6% and that of ETGD cytology was 59.1%.
In the comparison of diagnostic effectiveness of cytologic diagnosis using samples of bile juice from the gallbladder collected by different methods, the sensitivities were 38.9% and 73.3% for the first and washed ETGD cytologies, respectively.
In the comparison of the diagnostic effectiveness of gallbladder bile juice cytology using samples collected for different forms of lesion and by different methods, the sensitivities were 38.9% and 73.3%, respectively, for the first and washed ETGD cytologies for flat gallbladder wall thickening, while it was impossible to diagnose for lesions of GB polyp.
Conclusion.
For diagnosis of gallbladder cancer, we consider that the ETGD cytology should be taken into consideration for lesions of flat gallbladder wall thickening, for which it is difficult to distinguish between benign and malignant lesions.
American Psychological Association (APA)
Itsuki, Hiroshi& Serikawa, Masahiro& Sasaki, Tamito& Ishii, Yasutaka& Tsushima, Ken& Furukawa, Yoshinari…[et al.]. 2018. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1165079
Modern Language Association (MLA)
Itsuki, Hiroshi…[et al.]. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer. Gastroenterology Research and Practice No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1165079
American Medical Association (AMA)
Itsuki, Hiroshi& Serikawa, Masahiro& Sasaki, Tamito& Ishii, Yasutaka& Tsushima, Ken& Furukawa, Yoshinari…[et al.]. Indication and Usefulness of Bile Juice Cytology for Diagnosis of Gallbladder Cancer. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1165079
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165079