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Lipid Profile in Tuberculosis Patients with and without Human Immunodeficiency Virus Infection
Joint Authors
Chala, Feyissa
Gebregziabher, Atsbeha
Gebremicael, Gebremedhin
Amare, Yemane
Wolde, Mistire
Kassa, Desta
Medhin, Girmay
Source
International Journal of Chronic Diseases
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-11-01
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Understanding whether the preceding low lipid profile leads to active tuberculosis (TB) or active TB leads to low lipid profile is crucial.
Methods.
Lipid profile concentrations were determined from 159 study participants composed of 93 active TB patients [44 HIV coinfected (HIV+TB+) and 49 HIV negative (HIV−TB+)], 41 tuberculin skin test (TST) positive cases [17 HIV coinfected (HIV+TST+) and 24 HIV negative (HIV−TST+)], and 25 healthy controls (HIV−TST−).
Cobas Integra 400 Plus was used to determine lipid profiles concentration level.
Results.
The concentrations of total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) in HIV−TB+ patients were significantly lower compared to HIV−TST+ and to HIV−TST− individuals.
Similarly, the concentrations of the TC, LDL-C, and HDL-C in HIV+TB+ were significantly lower compared to HIV−TB+ patients.
After the 6 months of anti-TB treatment (ATT), the concentration levels of TC, LDL-C, and HDL-C in HIV−TB+ patients were higher compared to the baseline concentration levels, while they were not significantly different compared to that of HIV−TST+ concentration.
Conclusion.
The low concentration of lipid profiles in TB patients may be a consequence of the disease and significantly increased in TB patients after treatment.
American Psychological Association (APA)
Gebremicael, Gebremedhin& Amare, Yemane& Chala, Feyissa& Gebregziabher, Atsbeha& Medhin, Girmay& Wolde, Mistire…[et al.]. 2017. Lipid Profile in Tuberculosis Patients with and without Human Immunodeficiency Virus Infection. International Journal of Chronic Diseases،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1165177
Modern Language Association (MLA)
Gebremicael, Gebremedhin…[et al.]. Lipid Profile in Tuberculosis Patients with and without Human Immunodeficiency Virus Infection. International Journal of Chronic Diseases No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1165177
American Medical Association (AMA)
Gebremicael, Gebremedhin& Amare, Yemane& Chala, Feyissa& Gebregziabher, Atsbeha& Medhin, Girmay& Wolde, Mistire…[et al.]. Lipid Profile in Tuberculosis Patients with and without Human Immunodeficiency Virus Infection. International Journal of Chronic Diseases. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1165177
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165177