Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity
Joint Authors
Xu, Guobin
Wu, Guangyao
Cheng, Jingyun
Xie, Hui
Yang, Hao
Wang, Ke
Source
Gastroenterology Research and Practice
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-07-22
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
Objective.
To explore the feasibility of computed tomography enterography (CTE) in the quantitative evaluation of the activity of Crohn’s disease (CD).
Methods.
There were 49 CD patients with whole clinical, enteroscopy, and CTE data to be analyzed retrospectively.
The patients were graded as inactive (0–2), mild (3–6), and moderate-severe group (>6) based on simplified endoscopic activity score for Crohn’s disease (SES-CD).
The differences in bowel wall thickening, mural hyperenhancement in the portal vein period, and the ΔCT values were analyzed among groups using ANOVA (analysis of variance) and q test.
Then, the parameters were correlated with SES-CD, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR).
Results.
In the 49 patients, 13 ones were inactive, 19 ones were mild, and 17 ones were moderate-severe; the thickness of bowel wall, mural hyperenhancement in the portal vein period, and ΔCT value among groups were all significantly different (P<0.001 in all).
Correlative analysis showed that compared with the SES-CD, the bowel wall thickening (r=0.564, P<0.001), mural hyperenhancement in the portal vein period (r=0.585, P<0.001), and ΔCT value (r=0.533, P<0.001) were moderately correlated.
Conclusion.
The mural hyperenhancement in the portal vein period, bowel wall thickening, and ΔCT value can accurately and quantitatively assess the activity of CD lesions and are potential visual biomarkers of CD lesions.
American Psychological Association (APA)
Cheng, Jingyun& Xie, Hui& Yang, Hao& Wang, Ke& Xu, Guobin& Wu, Guangyao. 2018. Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1165499
Modern Language Association (MLA)
Cheng, Jingyun…[et al.]. Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity. Gastroenterology Research and Practice No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1165499
American Medical Association (AMA)
Cheng, Jingyun& Xie, Hui& Yang, Hao& Wang, Ke& Xu, Guobin& Wu, Guangyao. Computed Tomography Enterography: Quantitative Evaluation on Crohn’s Disease Activity. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1165499
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165499