Gene Identification and Characterization of Correlations for DEPs_DEGs Same Trend Responding to Salinity Adaptation in Scylla paramamosain
Joint Authors
Wang, Huan
Wei, Hongling
Tang, Lei
Lu, Junkai
Mu, Changkao
Wang, Chunlin
Source
International Journal of Genomics
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-10
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Scylla paramamosain is a commercially important species distributed along the coast of southern China and other Indo-Pacific countries.
Sudden salinity drop exceeding the adjustment capability of S.
paramamosain can result in damage or even mortality.
In our previous study, we had analyzed the mechanism of adapting sudden drop in salinity from the level of transcriptomics and proteomics, respectively.
This study performed a correlation analysis of RNA sequencing transcriptomics and iTRAQ proteomics in order to investigate the adaptation mechanisms to sudden salinity drop from 23‰ to 3‰.
There were 3954 correlations and a total of 15 correlations for differentially expressed proteins (DEPs) and differentially expressed genes (DEGs) from proteomics and transcriptomics.
The correlation between DEPs and DEGs was 0, and the Spearman correlation coefficient of the same trend correlation for DEPs and DEGs was the highest, reaching 0.9080.
KEGG pathway enrichment correlation revealed that protein digestion and absorption (Ko04974), proximal tubule bicarbonate (Ko04964), and bile secretion (Ko04976) played important roles in Na+/H+ and Na+/K+ exchange.
In addition, important genes related to osmoregulation, such as ion transport and carbonic anhydrase, were also detected in the correlation analysis for same trend DEPs_DEGs.
In conclusion, the proteome and transcriptome correlation results from this study indicate that ion transport plays a critical role in the adaptation of S.
paramamosain to sudden reduction in salinity.
American Psychological Association (APA)
Wang, Huan& Wei, Hongling& Tang, Lei& Lu, Junkai& Mu, Changkao& Wang, Chunlin. 2019. Gene Identification and Characterization of Correlations for DEPs_DEGs Same Trend Responding to Salinity Adaptation in Scylla paramamosain. International Journal of Genomics،Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1165756
Modern Language Association (MLA)
Wang, Huan…[et al.]. Gene Identification and Characterization of Correlations for DEPs_DEGs Same Trend Responding to Salinity Adaptation in Scylla paramamosain. International Journal of Genomics No. 2019 (2019), pp.1-12.
https://search.emarefa.net/detail/BIM-1165756
American Medical Association (AMA)
Wang, Huan& Wei, Hongling& Tang, Lei& Lu, Junkai& Mu, Changkao& Wang, Chunlin. Gene Identification and Characterization of Correlations for DEPs_DEGs Same Trend Responding to Salinity Adaptation in Scylla paramamosain. International Journal of Genomics. 2019. Vol. 2019, no. 2019, pp.1-12.
https://search.emarefa.net/detail/BIM-1165756
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165756