Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution
Joint Authors
Bao, Qiyu
Xu, Teng
Ying, Jianchao
Ye, Jun
Wang, Qian
Li, Aifang
Source
International Journal of Genomics
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-14, 14 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-12-20
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
Rhodococcus equi, a member of the Rhodococcus genus, is a gram-positive pathogenic bacterium.
Rhodococcus possesses an open pan-genome that constitutes the basis of its high genomic diversity and allows for adaptation to specific niche conditions and the changing host environments.
Our analysis further showed that the core genome of R.
equi contributes to the pathogenicity and niche adaptation of R.
equi.
Comparative genomic analysis revealed that the genomes of R.
equi shared identical collinearity relationship, and heterogeneity was mainly acquired by means of genomic islands and prophages.
Moreover, genomic islands in R.
equi were always involved in virulence, resistance, or niche adaptation and possibly working with prophages to cause the majority of genome expansion.
These findings provide an insight into the genomic diversity, evolution, and structural variation of R.
equi and a valuable resource for functional genomic studies.
American Psychological Association (APA)
Ying, Jianchao& Ye, Jun& Xu, Teng& Wang, Qian& Bao, Qiyu& Li, Aifang. 2019. Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution. International Journal of Genomics،Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1165780
Modern Language Association (MLA)
Ying, Jianchao…[et al.]. Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution. International Journal of Genomics No. 2019 (2019), pp.1-14.
https://search.emarefa.net/detail/BIM-1165780
American Medical Association (AMA)
Ying, Jianchao& Ye, Jun& Xu, Teng& Wang, Qian& Bao, Qiyu& Li, Aifang. Comparative Genomic Analysis of Rhodococcus equi: An Insight into Genomic Diversity and Genome Evolution. International Journal of Genomics. 2019. Vol. 2019, no. 2019, pp.1-14.
https://search.emarefa.net/detail/BIM-1165780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165780