Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus
Joint Authors
Tang, Yunzhao
Yan, Tiantian
Wang, Gang
Chen, Yijun
Zhu, Yanjuan
Jiang, Zhenhuan
Yang, Min
Li, Chenguang
Li, Zhu
Yu, Ping
Wang, Shanshan
Zhu, Nannan
Ren, Qiuyue
Ni, Changlin
Source
International Journal of Endocrinology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-10-12
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Objective.
The present study explored the association between insulin resistance (IR) and the clinical characteristics of thyroid nodules in patients with type 2 diabetes mellitus (T2DM).
Methods.
All the patients were newly diagnosed with T2DM.
201 patients with thyroid nodule disease and 308 patients without the nodular thyroid disease.
The participants were evaluated by relevant examination.
Correlation analyses and regression analyses were performed to examine the relationships between the two groups.
Results.
HOMA-IR values, serum FT4 (free thyroxine) levels, and age were higher in the thyroid nodule group than in the control group.
The proportion of women in the thyroid nodule group is greater than the proportion of women in the control group.
Logistic regression analysis showed that age, sex, FT4, and HOMA-IR were positive factors for thyroid nodule.
The volume and size of the thyroid nodule were positively correlated with HOMA-IR, irrespective of gender.
The thyroid nodule volume and size and the TSH (thyroid stimulating hormone) were greater in females than in males, whereas FT3 (free triiodothyronine) was lower in females.
Conclusion.
IR might be a risk factor for thyroid nodule.
Whether alleviating the IR might slow the growth, or diminish the volume and size of the thyroid nodules, is yet to be elucidated.
American Psychological Association (APA)
Tang, Yunzhao& Yan, Tiantian& Wang, Gang& Chen, Yijun& Zhu, Yanjuan& Jiang, Zhenhuan…[et al.]. 2017. Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1165992
Modern Language Association (MLA)
Tang, Yunzhao…[et al.]. Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus. International Journal of Endocrinology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1165992
American Medical Association (AMA)
Tang, Yunzhao& Yan, Tiantian& Wang, Gang& Chen, Yijun& Zhu, Yanjuan& Jiang, Zhenhuan…[et al.]. Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1165992
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1165992