Cost-Effectiveness of More Intensive Blood Pressure Treatment in Patients with High Risk of Cardiovascular Disease in Saudi Arabia: A Modelling Study of Meta-Analysis
Joint Authors
Almalki, Ziyad
Alatawi, Yasser
Alharbi, Adnan
Almaklefi, Bader
Alfaiz, Suliman
Almohana, Omar
Alsaidan, Yasser
Alanezi, Abdullah
Source
International Journal of Hypertension
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-09-30
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
The current literature suggests that more intensive blood pressure (BP) treatment is clinically more effective than less intensive treatment in patients at high risk for cardiovascular disease (CVD).
In this analysis, we evaluated the potential clinical benefit and cost-effectiveness of more intensive BP treatment in patients at high risk of developing CVD over their lifetimes.
Methods.
A Markov state-transition model was developed for the BP strategies to estimate the lifetime incremental cost-effectiveness ratio (ICER) per quality-adjusted-life-year (QALY) using evidence published from a meta-analysis.
The other model inputs were retrieved from previous studies.
Estimated costs were collected from five hospitals in Riyadh.
The model used a lifetime framework adopting Saudi payer perspective and applied a 3% annual discount rate.
Sensitivity analysis was conducted using one-way and probabilistic sensitivity analysis (PSA) to evaluate the robustness and uncertainty of the estimates.
Results.
Treating 10,000 patients with high CVD risk with more intensive BP therapy would avert a total of 873 CV events over their remaining lifetimes as compared with a less intensive strategy.
The projections showed that more intensive BP therapy would be cost-effective compared to the less intensive strategy with incremental costs per QALY of $20,358.
Probabilistic sensitivity analysis suggested more intensive control would be cost-effective compared with the less intensive control of BP 87.25 % of the time.
Conclusion.
The result of this study showed that more intensive BP treatment appears to be a cost-effective choice for patients with a high risk of CVD in Saudi Arabia when compared with a less intensive BP strategy.
Thus, this finding provides strong evidence for the adoption of this strategy within the Saudi healthcare system.
American Psychological Association (APA)
Almalki, Ziyad& Alatawi, Yasser& Alharbi, Adnan& Almaklefi, Bader& Alfaiz, Suliman& Almohana, Omar…[et al.]. 2019. Cost-Effectiveness of More Intensive Blood Pressure Treatment in Patients with High Risk of Cardiovascular Disease in Saudi Arabia: A Modelling Study of Meta-Analysis. International Journal of Hypertension،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166021
Modern Language Association (MLA)
Almalki, Ziyad…[et al.]. Cost-Effectiveness of More Intensive Blood Pressure Treatment in Patients with High Risk of Cardiovascular Disease in Saudi Arabia: A Modelling Study of Meta-Analysis. International Journal of Hypertension No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1166021
American Medical Association (AMA)
Almalki, Ziyad& Alatawi, Yasser& Alharbi, Adnan& Almaklefi, Bader& Alfaiz, Suliman& Almohana, Omar…[et al.]. Cost-Effectiveness of More Intensive Blood Pressure Treatment in Patients with High Risk of Cardiovascular Disease in Saudi Arabia: A Modelling Study of Meta-Analysis. International Journal of Hypertension. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166021