Prevalence and Clinical Significance of Streptococcus dysgalactiae subspecies equisimilis (Groups C or G Streptococci)‎ Colonization in Pregnant Women: A Retrospective Cohort Study

Abstract EN

Objectives.

Little is known about the significance of Streptococcus G or C colonization in pregnant women.

The objective of this study was to assess whether vaginal Streptococcus group G or C colonization detected in late pregnancy increases the infectious morbidity of the mother or newborn.

Methods.

A total of 15,114 rectovaginal cultures taken at 35–37 weeks of pregnancy were analyzed at Tampere University Hospital, Finland, between 2012 and 2014.

From this laboratory data, all Streptococcus G or C-positive cultures were included to study maternal and neonatal infectious morbidity after delivery.

This study population was compared to women with a positive Streptococcus B culture and to women with a negative culture.

Results.

The prevalence of Streptococcus G or C colonization was 2.9%.

Significantly more postpartum endometritis was found in this study group.

No association was found between colonization and neonatal bacteremia.

Conclusions.

Streptococcus G or C colonization is associated with postpartum endometritis.

More research is needed to clarify if antibiotic prophylaxis is reasonable for this group during delivery.