Safety and Efficacy of a New Renal Denervation Catheter in Hypertensive Patients in the Absent of Antihypertensive Medications: A Pilot Study
Joint Authors
Ma, Genshan
Li, Yang
Nawabi, Abdul Qadir
Feng, Yi
Dai, Qiming
Liu, Naifeng
Source
International Journal of Hypertension
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-4, 4 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-02-14
Country of Publication
Egypt
No. of Pages
4
Main Subjects
Abstract EN
Aim.
The aim of present study was to determine the safety and efficacy of a new renal artery denervation system for treatment of hypertensive patients.
Methods.
Hypertensive patients with mean office systolic blood pressure ≥150mmHg and ≤180mmHg or an average of 24-hour ambulatory systolic blood pressure ≥145mmHg and ≤170mmHg after stopping hypertensive medications for 2 weeks or more were enrolled to undergo renal denervation (RDN) using a new RDN system.
Changes in office blood pressure and mean 24-hour ambulatory blood pressure and safety were assessed after 6 months.
Results.
Fifteen patients underwent RDN and followed up for 6 months.
At the 6-month follow-up, office systolic blood pressure decreased 11.5±9.9mmHg (P<0.01) and office diastolic blood pressure decreased 6.9±4.8mmHg (P<0.01); mean 24-hour ambulatory systolic blood pressure decreased 7.5±7.7mmHg (P<0.05) and mean 24-hour diastolic blood pressure decreased 3.3±4.7mmHg (P>0.05) compared to baseline values.
There were no serious RDN-related adverse events during follow-up.
Conclusion.
Our results demonstrate that the new RDN system is safe and could significantly reduce blood pressure in hypertensive patients in the absence of antihypertensive medications.
This trial is registered with ChiCTR1800017815.
American Psychological Association (APA)
Li, Yang& Nawabi, Abdul Qadir& Feng, Yi& Dai, Qiming& Ma, Genshan& Liu, Naifeng. 2019. Safety and Efficacy of a New Renal Denervation Catheter in Hypertensive Patients in the Absent of Antihypertensive Medications: A Pilot Study. International Journal of Hypertension،Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1166059
Modern Language Association (MLA)
Li, Yang…[et al.]. Safety and Efficacy of a New Renal Denervation Catheter in Hypertensive Patients in the Absent of Antihypertensive Medications: A Pilot Study. International Journal of Hypertension No. 2019 (2019), pp.1-4.
https://search.emarefa.net/detail/BIM-1166059
American Medical Association (AMA)
Li, Yang& Nawabi, Abdul Qadir& Feng, Yi& Dai, Qiming& Ma, Genshan& Liu, Naifeng. Safety and Efficacy of a New Renal Denervation Catheter in Hypertensive Patients in the Absent of Antihypertensive Medications: A Pilot Study. International Journal of Hypertension. 2019. Vol. 2019, no. 2019, pp.1-4.
https://search.emarefa.net/detail/BIM-1166059
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166059