The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS)
Joint Authors
Yu, Chengdong
Zhao, Hongjun
Pan, Li
Zhang, Jia
Wang, Xiaoyang
Chang, Lijun
Tuo, Ya
Xi, Jin’en
Liu, Bin
Wang, Ye
Ren, Huiru
He, Huijing
Ren, Xiaolan
Shan, Guangliang
Source
International Journal of Hypertension
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-06-18
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Objective.
To estimate the additive interaction of body mass index (BMI) and family history of hypertension (FHH) on hypertension and explore whether the interaction could be influenced by behavioural risk factors.
Methods.
The cross-sectional data on 5791 participants were from the China National Health Survey in Gansu province in 2016.
We assessed the additive interaction by calculating the relative excess risk due to interaction (RERI), the attributable proportion due to interaction (AP), and the synergy index (SI).
Results.
ORs for hypertension were highest in Han (13.52, 95% CI: 9.45 to 19.34) and Yugur (13.85, 95% CI: 8.48 to 22.63) with the combination of obesity and FHH.
The interaction of BMI and FHH was significant in Han people, with the RERI, AP, and SI and their 95% CIs being 2.48 (1.13 to 3.82), 0.33 (0.19 to 0.47), and 1.61 (1.26 to 2.07) for overweight and FHH and 6.32 (1.91 to 10.73), 0.47 (0.27 to 0.67), and 2.02 (1.33 to 3.07) for obesity and FHH, respectively.
The interaction of BMI and FHH was not significant in Yugur people.
Adjustment for behavioural risk factors had little influence on the interactions, and risks of hypertension remained increased.
Conclusions.
BMI and FHH were associated with hypertension, and the interaction of BMI and FHH on hypertension was significant in Han but not in Yugur people.
Behavioural risk factors had little influence on the associations and interactions.
The exacerbation of hypertension risks by overweight or obesity in hypertension families deserves attention in weight control and community care.
American Psychological Association (APA)
Yu, Chengdong& Zhao, Hongjun& Pan, Li& Zhang, Jia& Wang, Xiaoyang& Chang, Lijun…[et al.]. 2019. The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS). International Journal of Hypertension،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166067
Modern Language Association (MLA)
Yu, Chengdong…[et al.]. The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS). International Journal of Hypertension No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1166067
American Medical Association (AMA)
Yu, Chengdong& Zhao, Hongjun& Pan, Li& Zhang, Jia& Wang, Xiaoyang& Chang, Lijun…[et al.]. The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS). International Journal of Hypertension. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1166067
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166067