Effect of Ethanol-Derived Clove Leaf Extract on the Oxidative Stress Response in Yeast Schizosaccharomyces pombe
Joint Authors
Fauzya, Anninda Faiz
Astuti, Rika Indri
Mubarik, Nisa Rachmania
Source
International Journal of Microbiology
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Compared to the widely explored antioxidant activity from the clove bud extract, less data are available regarding the potential pharmacological use of clove leaves.
Our study aimed to explore the antioxidant activity of clove leaves extract in the cellular level.
Thus, we used the yeast Schizosaccharomyces pombe as model organisms.
Our data indicate that, following extract treatment (100 ppm), the viability of the stationary phase cells of S.
pombe was higher than without extract and that of calorie restriction treatments.
100 ppm extract treatment also increased cell viability against H2O2-induced oxidative stress.
Those data indicate that the extract could promote oxidative stress tolerance response in yeast cells, which occurred either during the stationary phase or due to exogenous exposure.
Higher dose of extract (500 ppm) showed opposite effects, as cell viability was lower than that without treatment.
Analysis toward the mitochondrial activity revealed that the extract did not induce mitochondrial activity unlike the calorie restriction treatment.
Based on our data, clove leaf extract promotes oxidative stress tolerance response in the yeast S.
pombe, independent to that mitochondrial adaptive ROS signaling which commonly occurs in calorie restriction-induced oxidative stress tolerance response.
American Psychological Association (APA)
Fauzya, Anninda Faiz& Astuti, Rika Indri& Mubarik, Nisa Rachmania. 2019. Effect of Ethanol-Derived Clove Leaf Extract on the Oxidative Stress Response in Yeast Schizosaccharomyces pombe. International Journal of Microbiology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1166179
Modern Language Association (MLA)
Fauzya, Anninda Faiz…[et al.]. Effect of Ethanol-Derived Clove Leaf Extract on the Oxidative Stress Response in Yeast Schizosaccharomyces pombe. International Journal of Microbiology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1166179
American Medical Association (AMA)
Fauzya, Anninda Faiz& Astuti, Rika Indri& Mubarik, Nisa Rachmania. Effect of Ethanol-Derived Clove Leaf Extract on the Oxidative Stress Response in Yeast Schizosaccharomyces pombe. International Journal of Microbiology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1166179
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166179