Clinical Presentation, Management, and Outcomes of Primary Hyperparathyroidism during Pregnancy
Joint Authors
Hu, Ya
Cui, Ming
Sun, Zhengyi
Su, Zhe
Gao, Xiang
Liao, Quan
Zhao, Yupei
Source
International Journal of Endocrinology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-25
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background.
Primary hyperparathyroidism (pHPT) in pregnancy is a rare event, but it poses a significant risk to mothers and fetuses.
The optimal treatment strategy remains controversial.
Methods.
We present a consecutive series of twelve pregnant women with pHPT.
Results.
Twelve women were diagnosed with pHPT during pregnancy or in the postpartum period.
Four of them presented no symptoms or mild symptoms.
Four patients experienced serious complications, including hypercalcaemic crisis, acute pancreatitis, and eclampsia.
Another four patients were identified postpartum as the result of neonatal convulsion with hypocalcaemia.
Minimally invasive parathyroidectomy (MIP) under cervical plexus block was successfully performed in 11 of them during pregnancy or postpartum.
The serum levels of ionized calcium and intact parathyroid hormone (iPTH) were much higher in patients with severe complications in this cohort than those in the group of patients with no symptoms or mild symptoms and patients who were diagnosed postpartum.
Conclusions.
MIP under cervical plexus block might be a safe and effective treatment for pregnant women with pHPT.
Even though both conservative and surgical treatments are applicable for most mothers and fetuses with asymptomatic and mild hyperparathyroidism, serious complications may have catastrophic consequences for both.
American Psychological Association (APA)
Hu, Ya& Cui, Ming& Sun, Zhengyi& Su, Zhe& Gao, Xiang& Liao, Quan…[et al.]. 2017. Clinical Presentation, Management, and Outcomes of Primary Hyperparathyroidism during Pregnancy. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1166180
Modern Language Association (MLA)
Hu, Ya…[et al.]. Clinical Presentation, Management, and Outcomes of Primary Hyperparathyroidism during Pregnancy. International Journal of Endocrinology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1166180
American Medical Association (AMA)
Hu, Ya& Cui, Ming& Sun, Zhengyi& Su, Zhe& Gao, Xiang& Liao, Quan…[et al.]. Clinical Presentation, Management, and Outcomes of Primary Hyperparathyroidism during Pregnancy. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1166180
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166180