Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MSMS Analysis
Joint Authors
Wu, Liming
Cao, Wei
Lei, Haiyan
Guo, Jianbo
Lv, Zhuo
Zhu, Xiaohong
Xue, Xiaofeng
Source
International Journal of Analytical Chemistry
Issue
Vol. 2018, Issue 2018 (31 Dec. 2018), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2018-01-01
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
This study reports an analytical method for the determination of nitroimidazole and quinolones in honey using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
A modified QuEChERS methodology was used to extract the analytes and determine veterinary drugs in honey by LC-MS/MS.
The linear regression was excellent at the concentration levels of 1–100 ng/mL in the solution standard curve and the matrix standard curve.
The recovery rates of nitroimidazole and quinolones were 4.4% to 59.1% and 9.8% to 46.2% with relative standard deviations (RSDs) below 5.2% and the recovery rates of nitroimidazole and quinolones by the matrix standard curve ranged from 82.0% to 117.8% and 79% to 115.9% with relative standard deviations (RSDs) lower than 6.3% in acacia and jujube honey.
The acacia and jujube honeys have stronger matrix inhibition effect to nitroimidazole and quinolones residue; the matrix inhibition effect of jujube honey is stronger than acacia honey.
The matrix standard curve can calibrate matrix effect effectively.
In this study, the detection method of antibiotics in honey can be applied to the actual sample.
The results demonstrated that the modified QuEChERS method combined with LC-MS/MS is a rapid, high, sensitive method for the analysis of nitroimidazoles and quinolones residues in honey.
American Psychological Association (APA)
Lei, Haiyan& Guo, Jianbo& Lv, Zhuo& Zhu, Xiaohong& Xue, Xiaofeng& Wu, Liming…[et al.]. 2018. Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MSMS Analysis. International Journal of Analytical Chemistry،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1166377
Modern Language Association (MLA)
Lei, Haiyan…[et al.]. Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MSMS Analysis. International Journal of Analytical Chemistry No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1166377
American Medical Association (AMA)
Lei, Haiyan& Guo, Jianbo& Lv, Zhuo& Zhu, Xiaohong& Xue, Xiaofeng& Wu, Liming…[et al.]. Simultaneous Determination of Nitroimidazoles and Quinolones in Honey by Modified QuEChERS and LC-MSMS Analysis. International Journal of Analytical Chemistry. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1166377
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166377