The Tissue-Selective Estrogen Complex (BazedoxifeneConjugated Estrogens) for the Treatment of Menopause
Joint Authors
Lello, Stefano
Capozzi, Anna
Scambia, Giovanni
Source
International Journal of Endocrinology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-12-05
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The tissue-selective estrogen complex (TSEC) pairs conjugated estrogens (CE) with a selective estrogen receptor modulator (SERM), bazedoxifene acetate (BZA).
A 2-year treatment with the TSEC improved vasomotor symptoms, quality of life, and vaginal atrophy in healthy postmenopausal women.
In addition, the TSEC prevented vertebral and hip bone loss without increasing mammographic density, breast tenderness, the risk of myocardial infarction, stroke, or venous thromboembolism.
Finally, the BZA 20 mg/CE 0.45 mg dose did not increase the risk of endometrial hyperplasia.
Based on these findings, the TSEC can be considered as a first-line treatment for symptomatic postmenopausal women.
American Psychological Association (APA)
Lello, Stefano& Capozzi, Anna& Scambia, Giovanni. 2017. The Tissue-Selective Estrogen Complex (BazedoxifeneConjugated Estrogens) for the Treatment of Menopause. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166402
Modern Language Association (MLA)
Lello, Stefano…[et al.]. The Tissue-Selective Estrogen Complex (BazedoxifeneConjugated Estrogens) for the Treatment of Menopause. International Journal of Endocrinology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1166402
American Medical Association (AMA)
Lello, Stefano& Capozzi, Anna& Scambia, Giovanni. The Tissue-Selective Estrogen Complex (BazedoxifeneConjugated Estrogens) for the Treatment of Menopause. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166402
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166402