The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review
Joint Authors
Grübler, Martin R.
Verheyen, Nicolas
Pilz, Stefan
van Ballegooijen, Adriana J.
Tomaschitz, Andreas
Source
International Journal of Endocrinology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-12
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Vitamins D and K are both fat-soluble vitamins and play a central role in calcium metabolism.
Vitamin D promotes the production of vitamin K-dependent proteins, which require vitamin K for carboxylation in order to function properly.
The purpose of this review is to summarize available evidence of the synergistic interplay between vitamins D and K on bone and cardiovascular health.
Animal and human studies suggest that optimal concentrations of both vitamin D and vitamin K are beneficial for bone and cardiovascular health as supported by genetic, molecular, cellular, and human studies.
Most clinical trials studied vitamin D and K supplementation with bone health in postmenopausal women.
Few intervention trials studied vitamin D and K supplementation with cardiovascular-related outcomes.
These limited studies indicate that joint supplementation might be beneficial for cardiovascular health.
Current evidence supports the notion that joint supplementation of vitamins D and K might be more effective than the consumption of either alone for bone and cardiovascular health.
As more is discovered about the powerful combination of vitamins D and K, it gives a renewed reason to eat a healthy diet including a variety of foods such as vegetables and fermented dairy for bone and cardiovascular health.
American Psychological Association (APA)
van Ballegooijen, Adriana J.& Pilz, Stefan& Tomaschitz, Andreas& Grübler, Martin R.& Verheyen, Nicolas. 2017. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1166564
Modern Language Association (MLA)
van Ballegooijen, Adriana J.…[et al.]. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. International Journal of Endocrinology No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1166564
American Medical Association (AMA)
van Ballegooijen, Adriana J.& Pilz, Stefan& Tomaschitz, Andreas& Grübler, Martin R.& Verheyen, Nicolas. The Synergistic Interplay between Vitamins D and K for Bone and Cardiovascular Health: A Narrative Review. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1166564
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166564