RGB Pixel Brightness Characteristics of Linked Color Imaging in Early Gastric Cancer: A Pilot Study
Joint Authors
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Background and Aims.
Linked color imaging (LCI) helps screen and diagnose for early gastric cancer by color contrast in different mucosa.
RGB (red, green, and blue) pixel brightness quantifies colors, which is relatively objective.
Limited studies have combined LCI images with RGB to help screen for early gastric cancer (EGC).
We aimed to evaluate the RGB pixel brightness characteristics of EGC and noncancer areas in LCI images.
Methods.
We retrospectively reviewed early gastric cancer (EGC) patients and LCI images.
All pictures were evaluated by at least two endoscopic physicians.
RGB pixel brightness analysis of LCI images was performed in MATLAB software to compare the cancer with noncancer areas.
Receiver operating characteristic (ROC) curve was analyzed for sensitivity, specificity, cut-off, and area under the curve (AUC).
Results.
Overall, 38 early gastric cancer patients were enrolled with 38 LCI images.
Pixel brightness of red, green, and blue in cancer was remarkably higher than those in noncancer areas (190.24±37.10 vs.
160.00±40.35, p<0.001; 117.96±33.91 vs.
105.33±30.01, p=0.039; 114.36±34.88 vs.
90.93±30.14, p<0.001, respectively).
Helicobacter plyori (Hp) infection was not relevant to RGB distribution of EGC.
Whether the score of Kyoto Classification of Gastritis (KCG) is ≥4 or <4, the pixel brightness of red, green, and blue was not disturbed in both cancer and noncancer (p>0.05).
Receiver operating characteristic (ROC) curve for differentiating cancer from noncancer was calculated.
The maximum area under the curve (AUC) was 0.767 in B/G, with a sensitivity of 0.605, a specificity of 0.921, and a cut-off of 0.97.
Conclusions.
RGB pixel brightness was useful and more objective in distinguishing early gastric cancer for LCI images.
American Psychological Association (APA)
Sun, Xue& Zhao, Li. 2020. RGB Pixel Brightness Characteristics of Linked Color Imaging in Early Gastric Cancer: A Pilot Study. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166689
Modern Language Association (MLA)
Sun, Xue& Zhao, Li. RGB Pixel Brightness Characteristics of Linked Color Imaging in Early Gastric Cancer: A Pilot Study. Gastroenterology Research and Practice No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1166689
American Medical Association (AMA)
Sun, Xue& Zhao, Li. RGB Pixel Brightness Characteristics of Linked Color Imaging in Early Gastric Cancer: A Pilot Study. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166689
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166689