The Role of Active Inflammation and Surgical Therapy in Crohn’s Disease Recurrence
Joint Authors
Sica, Giuseppe S.
Divizia, A.
Arcudi, C.
Ingallinella, S.
Campanelli, M.
Antonelli, A.
Bellato, V.
Franceschilli, M.
Petagna, L.
Sensi, B.
Sibio, S.
Siragusa, L.
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-6, 6 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-12-29
Country of Publication
Egypt
No. of Pages
6
Main Subjects
Abstract EN
An altered balance between effector and regulatory factors is supposed to sustain the tissue-damaging immune response in inflammatory bowel disease (IBD).
Several studies demonstrate that severe active inflammation is a strong predictor for surgical complications and recurrence.
Indeed, bowel resection in Crohn’s disease (CD) patients has a high surgical recurrence rate.
In this review, we examined the IBD inflammatory pathways, the current surgical treatments, and the almost inevitable recurrence.
The question that might arise is if the cure of intestinal CD is to be found in the surgical approach.
A selective search of two databases (PubMed and the Cochrane Library) has been carried out without considering a specific time horizon as inclusion criteria.
The scope of this literature review was investigating on the role of inflammation in the management of CD.
The following key words have been used to develop the query string: (i) inflammation; (ii) Crohn’s disease; (iii) surgery; and (iv) postsurgical recurrence.
American Psychological Association (APA)
Ingallinella, S.& Campanelli, M.& Antonelli, A.& Arcudi, C.& Bellato, V.& Divizia, A.…[et al.]. 2020. The Role of Active Inflammation and Surgical Therapy in Crohn’s Disease Recurrence. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1166735
Modern Language Association (MLA)
Ingallinella, S.…[et al.]. The Role of Active Inflammation and Surgical Therapy in Crohn’s Disease Recurrence. Gastroenterology Research and Practice No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1166735
American Medical Association (AMA)
Ingallinella, S.& Campanelli, M.& Antonelli, A.& Arcudi, C.& Bellato, V.& Divizia, A.…[et al.]. The Role of Active Inflammation and Surgical Therapy in Crohn’s Disease Recurrence. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1166735
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166735