Clinicopathological Features of Advanced Gastric Cancers which Were Misjudged and Subjected to Endoscopic Submucosal Dissection
Joint Authors
Inoshita, Naoko
Kikuchi, Daisuke
Hoteya, Shu
Yamashita, Satoshi
Nomura, Kosuke
Tanaka, Masami
Ochiai, Yorinari
Hayasaka, Junnosuke
Suzuki, Yugo
Odagiri, Hiroyuki
Iizuka, Toshiro
Kitagawa, Masanobu
Matsui, Akira
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-02
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background and Aims.
Endoscopic submucosal dissection (ESD) is widely performed for early gastric cancer (EGC).
We have sometimes encountered gastric cancer lesions for which ESD was performed and at which pathologically advanced cancer was found.
In this study, we performed clinicopathological examination of lesions whose endoscopic diagnosis and pathology differed substantially.
Methods.
ESD was performed for 2,194 gastric cancer lesions (1,753 cases) in our institute from April 2005 through March 2015.
The vertical margin was positive or status unknown in 51 lesions (2.3%); among these, muscularis propria (MP) or deeper infiltration was identified in 6 lesions from specimens obtained during subsequent surgery.
In 1 lesion with MP invasion, the vertical margin was negative.
We evaluated the clinicopathological features of these 7 lesions and retrospectively reviewed endoscopic indicators of submucosal invasion for EGC on white light imaging (WLI), narrow-band imaging magnifying endoscopy (NBI-ME), and endoscopic ultrasonography (EUS) performed previously.
Results.
Average age was 73.2±7.2 years, and all cases were men.
The 7 lesions diagnosed as advanced cancer were 0.32% of 2,194 lesions and were all located in the U region (fundus).
On retrospective review of endoscopic findings, 2 of 7 lesions on WBI, 3 of 6 lesions on NBI-ME, and 2 of 5 lesions on EUS met the criteria for indicating submucosal invasion of EGC.
No lesions had findings on all 3 modalities.
Conclusion.
In rare cases, advanced gastric cancer could not be accurately diagnosed by endoscopy using various modalities.
Each case had special characteristics making identification of deep infiltration difficult.
American Psychological Association (APA)
Ochiai, Yorinari& Kikuchi, Daisuke& Inoshita, Naoko& Hayasaka, Junnosuke& Suzuki, Yugo& Tanaka, Masami…[et al.]. 2020. Clinicopathological Features of Advanced Gastric Cancers which Were Misjudged and Subjected to Endoscopic Submucosal Dissection. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166943
Modern Language Association (MLA)
Ochiai, Yorinari…[et al.]. Clinicopathological Features of Advanced Gastric Cancers which Were Misjudged and Subjected to Endoscopic Submucosal Dissection. Gastroenterology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1166943
American Medical Association (AMA)
Ochiai, Yorinari& Kikuchi, Daisuke& Inoshita, Naoko& Hayasaka, Junnosuke& Suzuki, Yugo& Tanaka, Masami…[et al.]. Clinicopathological Features of Advanced Gastric Cancers which Were Misjudged and Subjected to Endoscopic Submucosal Dissection. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166943