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The Predictive and Prognostic Factors in Patients with Gastric Cancer Accompanied by Gastric Outlet Obstruction
Joint Authors
Xue, Yingwei
Zu, Hongliang
Wang, Huiling
Li, Chunfeng
Zhu, Wendian
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-07-25
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Purpose.
This study is aimed at evaluating the clinicopathological features and prognostic significance of gastric outlet obstruction (GOO) in patients with distal gastric cancer.
Methods.
A retrospective review of 1564 individuals with distal gastric cancer from 2002 to 2010 was performed.
In total, 157 patients had GOO.
The clinicopathological features of the patients with GOO were compared with those of the patients without GOO.
A Kaplan-Meier survival analysis and Cox proportional hazard model were used to assess the overall survival.
Results.
The patients with distal gastric cancer with GOO generally presented more aggressive pathologic features, a poorer nutritional status, more duodenal infiltration, and peritoneal dissemination than those with cancer without GOO.
In the univariate analysis, curability, GOO, age, prealbumin, albumin, hemoglobin (Hb), the tumor size, the macroscopic type, lymph node metastasis, and the depth of invasion had a statistically significant influence on prognosis.
The multivariate analysis showed that curability, GOO, the tumor size, lymph node metastasis, and the depth of invasion were independent prognostic factors.
Conclusions.
Gastric cancer with GOO exhibits aggressive biological features and has poor outcomes.
The multivariate analysis showed that curability, GOO, the tumor size, lymph node metastasis, and the depth of invasion were independent prognostic factors.
The gastric outlet status should be considered in the selection of surgical treatment methods for patients with gastric cancer.
American Psychological Association (APA)
Zu, Hongliang& Wang, Huiling& Li, Chunfeng& Zhu, Wendian& Xue, Yingwei. 2020. The Predictive and Prognostic Factors in Patients with Gastric Cancer Accompanied by Gastric Outlet Obstruction. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166945
Modern Language Association (MLA)
Zu, Hongliang…[et al.]. The Predictive and Prognostic Factors in Patients with Gastric Cancer Accompanied by Gastric Outlet Obstruction. Gastroenterology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1166945
American Medical Association (AMA)
Zu, Hongliang& Wang, Huiling& Li, Chunfeng& Zhu, Wendian& Xue, Yingwei. The Predictive and Prognostic Factors in Patients with Gastric Cancer Accompanied by Gastric Outlet Obstruction. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166945
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166945