The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies
Joint Authors
Shyr, Yu
Lehmann, Brian
Zhang, Pan
Guo, Yan
Source
International Journal of Genomics
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-26
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
High throughput genomic assays empower us to study the entire human genome in short time with reasonable cost.
Formalin fixed-paraffin-embedded (FFPE) tissue processing remains the most economical approach for longitudinal tissue specimen storage.
Therefore, the ability to apply high throughput genomic applications to FFPE specimens can expand clinical assays and discovery.
Many studies have measured the accuracy and repeatability of data generated from FFPE specimens using high throughput genomic assays.
Together, these studies demonstrate feasibility and provide crucial guidance for future studies using FFPE specimens.
Here, we summarize the findings of these studies and discuss the limitations of high throughput data generated from FFPE specimens across several platforms that include microarray, high throughput sequencing, and NanoString.
American Psychological Association (APA)
Zhang, Pan& Lehmann, Brian& Shyr, Yu& Guo, Yan. 2017. The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies. International Journal of Genomics،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166994
Modern Language Association (MLA)
Zhang, Pan…[et al.]. The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies. International Journal of Genomics No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1166994
American Medical Association (AMA)
Zhang, Pan& Lehmann, Brian& Shyr, Yu& Guo, Yan. The Utilization of Formalin Fixed-Paraffin-Embedded Specimens in High Throughput Genomic Studies. International Journal of Genomics. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166994
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1166994