Effect of Gender and Age on the Correlation between Helicobacter pylori and Colorectal Adenomatous Polyps in a Chinese Urban Population: A Single Center Study
Joint Authors
Zhao, Xia-Xia
Liu, Ming-Hao
Wang, Rui-Ling
Tian, Tian
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-02-10
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objectives.
To investigate whether Helicobacter pylori (H.
pylori) infection increases the risk of colorectal adenomatous polyp (CAP) in the context of age and gender.
Methods.
A total of 563 study subjects (male/female, 368/195) from Beijing, China, with higher nursing level who underwent colonoscopy were retrospectively collected.
H.
pylori and CAP were detected by carbon-13 urea breath test and colorectal colonoscopy.
The correlations between the number, size, distribution, and pathological grade of CAP and H.
pylori infection were analyzed.
The population was further stratified by age and gender in order to examine the risk of H.
pylori and CAP in the context of these variables.
The influence of H.
pylori on the risk of CAP was assessed by logistic regression model.
Results.
315 participants were diagnosed with CAP, and 207 participants were classified as healthy controls.
The prevalence of H.
pylori in the CAP group was significantly higher than that in the healthy control group (119/315, 37.8% versus 44/207, 21.3%) (p<0.001).
The proportion of H.
pylori positive plus CAP in participants <50 years old was significantly higher than that in participants >50 years old (87/250; 34.8% versus 32/65; 49.2%) (p=0.033).
Furthermore, H.
pylori infection was identified as one of the major risk factors of CAP (OR=2.679; 95% CI: 1.717-4.179, p<0.001), independent of age, sex, and body mass index and was correlated with size, distribution, and pathological grading of CAP (p<0.001).
Conclusions.
H.
pylori is a major risk factor for CAP.
Further studies are needed to assess the effects of H.
pylori treatment or persistent infection on the occurrence or recurrence of CAP.
American Psychological Association (APA)
Zhao, Xia-Xia& Liu, Ming-Hao& Wang, Rui-Ling& Tian, Tian. 2020. Effect of Gender and Age on the Correlation between Helicobacter pylori and Colorectal Adenomatous Polyps in a Chinese Urban Population: A Single Center Study. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1167062
Modern Language Association (MLA)
Zhao, Xia-Xia…[et al.]. Effect of Gender and Age on the Correlation between Helicobacter pylori and Colorectal Adenomatous Polyps in a Chinese Urban Population: A Single Center Study. Gastroenterology Research and Practice No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1167062
American Medical Association (AMA)
Zhao, Xia-Xia& Liu, Ming-Hao& Wang, Rui-Ling& Tian, Tian. Effect of Gender and Age on the Correlation between Helicobacter pylori and Colorectal Adenomatous Polyps in a Chinese Urban Population: A Single Center Study. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1167062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167062