Evidence according to Cochrane Systematic Reviews on Alterable Risk Factors for Anastomotic Leakage in Colorectal Surgery
Joint Authors
Wallace, Bradley
Schuepbach, Fabia
Gaukel, Stefan
Marwan, Ahmed I.
Staerkle, Ralph F.
Vuille-dit-Bille, Raphael N.
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-15, 15 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-03
Country of Publication
Egypt
No. of Pages
15
Main Subjects
Abstract EN
Anastomotic leakage reflects a major problem in visceral surgery, leading to increased morbidity, mortality, and costs.
This review is aimed at evaluating and summarizing risk factors for colorectal anastomotic leakage.
A generalized discussion first introduces risk factors beginning with nonalterable factors.
Focus is then brought to alterable impact factors on colorectal anastomoses, utilizing Cochrane systematic reviews assessed via systemic literature search of the Cochrane Central Register of Controlled Trials and Medline until May 2019.
Seventeen meta-anaylses covering 20 factors were identified.
Thereof, 7 factors were preoperative, 10 intraoperative, and 3 postoperative.
Three factors significantly reduced the incidence of anastomotic leaks: high (versus low) surgeon’s operative volume (RR=0.68), stapled (versus handsewn) ileocolic anastomosis (RR=0.41), and a diverting ostomy in anterior resection for rectal carcinoma (RR=0.32).
Discussion of all alterable factors is made in the setting of the pre-, intra-, and postoperative influencers, with the only significant preoperative risk modifier being a high colorectal volume surgeon and the only significant intraoperative factors being utilizing staples in ileocolic anastomoses and a diverting ostomy in rectal anastomoses.
There were no measured postoperative alterable factors affecting anastomotic integrity.
American Psychological Association (APA)
Wallace, Bradley& Schuepbach, Fabia& Gaukel, Stefan& Marwan, Ahmed I.& Staerkle, Ralph F.& Vuille-dit-Bille, Raphael N.. 2020. Evidence according to Cochrane Systematic Reviews on Alterable Risk Factors for Anastomotic Leakage in Colorectal Surgery. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1167113
Modern Language Association (MLA)
Wallace, Bradley…[et al.]. Evidence according to Cochrane Systematic Reviews on Alterable Risk Factors for Anastomotic Leakage in Colorectal Surgery. Gastroenterology Research and Practice No. 2020 (2020), pp.1-15.
https://search.emarefa.net/detail/BIM-1167113
American Medical Association (AMA)
Wallace, Bradley& Schuepbach, Fabia& Gaukel, Stefan& Marwan, Ahmed I.& Staerkle, Ralph F.& Vuille-dit-Bille, Raphael N.. Evidence according to Cochrane Systematic Reviews on Alterable Risk Factors for Anastomotic Leakage in Colorectal Surgery. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-15.
https://search.emarefa.net/detail/BIM-1167113
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167113