Immune Response in H. pylori-Associated Gastritis and Gastric Cancer
Joint Authors
Hu, Bao-guang
Zhu, Jun
Niu, Qingbin
Yu, Xingquan
Feng, Tao
Ji, Hong
Li, Yuming
Zhang, Weiwei
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-01-28
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Helicobacter pylori (H.
pylori) is the dominant member of the gastric microbiota and has infected more than half of the human population, of whom 5–15% develop gastric diseases ranging from gastritis and metaplasia to gastric cancer.
These diseases always follow inflammation induced by cell surface and intracellular receptors and subsequent signaling, such as the NF-κB pathway and inflammasomes.
Some types of immune cells are recruited to enforce an antibacterial response, which could be impeded by H.
pylori virulence factors with or without a specific immune cell.
Following decreased inflammation, neoplasm may appear with a little immune surveillance and may inhibit antitumor immunity.
Therefore, the balance between H.
pylori-associated inflammation and anti-inflammation is crucial for human health and remains to be determined.
Here, we discuss multiple inflammation and immunoregulatory cells in gastritis and summarize the main immune evasion strategies employed by gastric cancer.
American Psychological Association (APA)
Niu, Qingbin& Zhu, Jun& Yu, Xingquan& Feng, Tao& Ji, Hong& Li, Yuming…[et al.]. 2020. Immune Response in H. pylori-Associated Gastritis and Gastric Cancer. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167157
Modern Language Association (MLA)
Niu, Qingbin…[et al.]. Immune Response in H. pylori-Associated Gastritis and Gastric Cancer. Gastroenterology Research and Practice No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1167157
American Medical Association (AMA)
Niu, Qingbin& Zhu, Jun& Yu, Xingquan& Feng, Tao& Ji, Hong& Li, Yuming…[et al.]. Immune Response in H. pylori-Associated Gastritis and Gastric Cancer. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167157
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167157