A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy
Joint Authors
Chun, Hoon Jai
Keum, Bora
Choi, Hyuk Soon
Kim, Eun Sun
Lee, Hong Sik
Kim, Chang Duck
Kim, Sang Hoon
Kim, Ji Hyeong
Jeon, Han Jo
Jang, Se Hyun
Choi, Seong Ji
Kim, Seung Han
Lee, Jae Min
Jeen, Yoon Tae
Source
Gastroenterology Research and Practice
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-03-03
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Patient compliance during bowel preparation is important for successful colonoscopy.
Bowel preparation with polyethylene glycol (PEG), the most commonly used solution for cleansing, involves the unpleasant ingestion of a large amount of liquid.
Sodium picosulfate magnesium citrate (SP-MC) solution is an alternative option with better palatability than PEG.
Therefore, in this study, we compared the efficacy and patient tolerability among the following three bowel preparation protocols: 2 L PEG-ascorbic acid (ASc), 1 L PEG-ASc plus bisacodyl, and SP-MC 340 mL plus bisacodyl.
We conducted a randomized prospective endoscopist-blinded study between August 2018 and January 2019.
A total of 311 patients were randomly classified into three groups according to the above-described bowel preparation protocols.
To evaluate the efficacy of bowel cleansing, we used the Boston Bowel Preparation Scale.
The degree of symptoms and the patients’ satisfaction with each bowel preparation method were investigated using a questionnaire completed before sedation for colonoscopy.
The baseline characteristics were similar among the three groups.
There was no significant difference in the bowel preparation quality among the three groups.
However, the incidence of symptoms, such as abdominal fullness and pain, was significantly lower (P=0.006 and 0.027, respectively) while the patients’ satisfaction rate was significantly higher (P=0.012) in the SP-MC plus bisacodyl group than in the two PEG groups.
In this study, the efficacy of the SP-MC plus bisacodyl solution was similar to that of the PEG solutions.
However, patient tolerability and satisfaction were better in the SP-MC plus bisacodyl group than in the other groups.
In conclusion, the use of SP-MC plus bisacodyl bowel preparation solution might be a better method for providing good intestinal cleansing and improving patient compliance.
American Psychological Association (APA)
Kim, Sang Hoon& Kim, Ji Hyeong& Keum, Bora& Jeon, Han Jo& Jang, Se Hyun& Choi, Seong Ji…[et al.]. 2020. A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1167173
Modern Language Association (MLA)
Kim, Sang Hoon…[et al.]. A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy. Gastroenterology Research and Practice No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1167173
American Medical Association (AMA)
Kim, Sang Hoon& Kim, Ji Hyeong& Keum, Bora& Jeon, Han Jo& Jang, Se Hyun& Choi, Seong Ji…[et al.]. A Randomized, Endoscopist-Blinded, Prospective Trial to Compare the Efficacy and Patient Tolerability between Bowel Preparation Protocols Using Sodium Picosulfate Magnesium Citrate and Polyethylene-Glycol (1 L and 2 L) for Colonoscopy. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1167173
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167173