Is Neutrophil-to-Lymphocyte Ratio a Predictor of Coronary Artery Disease in Western Indians?
Joint Authors
Shah, Komal H.
Sharma, Kamal H.
Konat, Ashwati R.
Patel, Alap K.
Source
International Journal of Inflammation
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-24
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
The current study was designed to evaluate the association of neutrophil-to-lymphocyte ratio (NLR) with coronary artery disease (CAD) presence.
We also aimed to propose a suitable cut-off of NLR for diagnosis of CAD in Western Indians.
Methods.
Total 324 patients undergoing coronary angiography were enrolled and were subdivided into two groups: group 1 (n=99; population without CAD) and group 2 (n=225; population with CAD).
Results.
The results indicated significant (p<0.05) positive association between elevated levels of WBC, neutrophil, monocyte, NLR, hs-CRP, CPK-MB, and troponin I and disease presence.
According to subgroup analysis, the association was more profound in male and older population.
Among all the markers NLR showed the strongest predictive potential for CAD with highest odds ratio (1.495; 95% CI: 0.942–2.371; p<0.048).
Optimum cut-off of NLR for diagnosis of CAD was 2.13 (AUC-0.823; p<0.001; sensitivity: 83.64%; specificity: 63.46%).
Association of NLR with other biochemical markers such as hs-CRP, CPK-MB, and troponin I was also observed in quartile analysis.
Conclusion.
NLR is a simple indicator that could be effectively used for the diagnosis of CAD with a cut-off of 2.13 in Western Indian population.
American Psychological Association (APA)
Sharma, Kamal H.& Patel, Alap K.& Shah, Komal H.& Konat, Ashwati R.. 2017. Is Neutrophil-to-Lymphocyte Ratio a Predictor of Coronary Artery Disease in Western Indians?. International Journal of Inflammation،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167444
Modern Language Association (MLA)
Sharma, Kamal H.…[et al.]. Is Neutrophil-to-Lymphocyte Ratio a Predictor of Coronary Artery Disease in Western Indians?. International Journal of Inflammation No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1167444
American Medical Association (AMA)
Sharma, Kamal H.& Patel, Alap K.& Shah, Komal H.& Konat, Ashwati R.. Is Neutrophil-to-Lymphocyte Ratio a Predictor of Coronary Artery Disease in Western Indians?. International Journal of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167444
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167444