The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism
Joint Authors
Source
International Journal of Inflammation
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-12, 12 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-03
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Abstract EN
Toll-like receptors (TLRs), part of the innate immune system that recognises molecular signatures, are important in the recognition of pathogenic components.
However, when specific cellular contexts develop in which TLRs are inappropriately activated by self-components, this may lead to sterile inflammation and result in the occurrence of autoimmunity.
This review analyses the available data regarding TLR biochemistry, the specific mechanisms which are brought about by TLR activation, and the importance of these mechanisms in the light of any existing and potential therapies in the field of autoimmunity.
American Psychological Association (APA)
Farrugia, Mark& Baron, Byron. 2017. The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism. International Journal of Inflammation،Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1167492
Modern Language Association (MLA)
Farrugia, Mark& Baron, Byron. The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism. International Journal of Inflammation No. 2017 (2017), pp.1-12.
https://search.emarefa.net/detail/BIM-1167492
American Medical Association (AMA)
Farrugia, Mark& Baron, Byron. The Role of Toll-Like Receptors in Autoimmune Diseases through Failure of the Self-Recognition Mechanism. International Journal of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-12.
https://search.emarefa.net/detail/BIM-1167492
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167492