Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?
Joint Authors
Kamaldin, Nurulain ‘Atikah
Sulaiman, Siti Amrah
Yusop, Rahimi M.
Yahaya, B.
Source
International Journal of Inflammation
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-11, 11 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-06-04
Country of Publication
Egypt
No. of Pages
11
Main Subjects
Abstract EN
Many studies have been done to evaluate the effect of various natural products in controlling asthma symptoms.
Virgin coconut oil (VCO) is known to contain active compounds that have beneficial effects on human health and diseases.
The objective of this study was to evaluate the effect of VCO inhalation on airway remodelling in a rabbit model of allergic asthma.
The effects of VCO inhalation on infiltration of airway inflammatory cells, airway structures, goblet cell hyperplasia, and cell proliferation following ovalbumin induction were evaluated.
Allergic asthma was induced by a combination of ovalbumin and alum injection and/or followed by ovalbumin inhalation.
The effect of VCO inhalation was then evaluated via the rescue or the preventive route.
Percentage of inflammatory cells infiltration, thickness of epithelium and mucosa regions, and the numbers of goblet and proliferative cells were reduced in the rescue group but not in preventive group.
Analysis using a gas chromatography-mass spectrometry found that lauric acid and capric acid were among the most abundant fatty acids present in the sample.
Significant improvement was observed in rescue route in alleviating the asthma symptoms, which indicates the VCO was able to relieve asthma-related symptoms more than preventing the onset of asthma.
American Psychological Association (APA)
Kamaldin, Nurulain ‘Atikah& Sulaiman, Siti Amrah& Yusop, Rahimi M.& Yahaya, B.. 2017. Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?. International Journal of Inflammation،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1167498
Modern Language Association (MLA)
Kamaldin, Nurulain ‘Atikah…[et al.]. Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?. International Journal of Inflammation No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1167498
American Medical Association (AMA)
Kamaldin, Nurulain ‘Atikah& Sulaiman, Siti Amrah& Yusop, Rahimi M.& Yahaya, B.. Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?. International Journal of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1167498
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167498