Production, Characterization, and Antimicrobial Activity of Mycocin Produced by Debaryomyces hansenii DSMZ70238
Joint Authors
Al-Haideri, Halah H.
Al-Qaysi, Safaa A. S.
Thabit, Zaid Akram
Al-Kubaisy, Wijdan Hameed Abd Al-Razzaq
Ibrahim, Jamal Abd Al-Rahman
Source
International Journal of Microbiology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-07-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
The present study was conducted to estimate the antimicrobial activity and the potential biological control of the killer toxin produced by D.
hansenii DSMZ70238 against several pathogenic microorganisms.
In this study, the effects of NaCl, pH, and temperature, killer toxin production, and antimicrobial activity were studied.
The results showed that the optimum inhibitory effect of killer toxin was at 8% NaCl, and the diameters of clear zones were 20, 22, 22, 21, 14, and 13 mm for Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Streptococcus pyogenes, Candida albicans, and Candida neoformans, respectively.
The largest inhibition zones were observed at pH 4.5 with inhibition zone of 16, 18, 17, 18, 11, and 12 mm for the same microorganisms.
The results also showed that 25°C is the optimal temperature for toxin killing activity against all targeted microorganisms.
In addition, the activity of killer toxin significantly inhibited the growth of fungal mycelia for all target pathogenic fungi and the percentages of inhibition were 47.77, 48.88, 52.22, and 61.11% for Trichophyton rubrum, Alternaria alternata, Trichophyton concentricum, and Curvularia lunata, respectively.
The results showed the highest growth rate of D.
hansenii DSMZ70238 under condition of 8% NaCl concentration, pH 4.5, and 25°C for 72 h.
American Psychological Association (APA)
Al-Qaysi, Safaa A. S.& Al-Haideri, Halah H.& Thabit, Zaid Akram& Al-Kubaisy, Wijdan Hameed Abd Al-Razzaq& Ibrahim, Jamal Abd Al-Rahman. 2017. Production, Characterization, and Antimicrobial Activity of Mycocin Produced by Debaryomyces hansenii DSMZ70238. International Journal of Microbiology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1167537
Modern Language Association (MLA)
Al-Qaysi, Safaa A. S.…[et al.]. Production, Characterization, and Antimicrobial Activity of Mycocin Produced by Debaryomyces hansenii DSMZ70238. International Journal of Microbiology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1167537
American Medical Association (AMA)
Al-Qaysi, Safaa A. S.& Al-Haideri, Halah H.& Thabit, Zaid Akram& Al-Kubaisy, Wijdan Hameed Abd Al-Razzaq& Ibrahim, Jamal Abd Al-Rahman. Production, Characterization, and Antimicrobial Activity of Mycocin Produced by Debaryomyces hansenii DSMZ70238. International Journal of Microbiology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1167537
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167537