Human Milk Oligosaccharides: The Journey Ahead
Joint Authors
Ray, Chandan
Kerketta, Joshi A.
Rao, Subhash
Patel, Snehal
Dutt, Shantanu
Arora, Kamal
Pournami, Femitha
Bhushan, Phani
Source
International Journal of Pediatrics
Issue
Vol. 2019, Issue 2019 (31 Dec. 2019), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2019-08-04
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Breast milk is a complex biological fluid that is rich in nutrients and bioactive agents that support the healthy growth and development of the newborns.
Human milk oligosaccharides (HMOs) are unconjugated glycans that constitute an important component of the protection conferred by breast milk on the neonate.
HMOs may act locally on the neonatal intestine by acting as signalling molecules and directly interacting with the host cells.
Although fucosylated and sialylated HMOs have little nutritional value, they exert important prebiotic as well as immunomodulatory effects on the infant gut.
However, there is heterogeneity in the quantity and quality of HMOs in breast milk produced by mothers under influence of the genetic and environmental factors.
This review encompasses the salient aspects of HMOs such as composition, function, structural diversity, and functional impact on the growth and survival of newborns.
In this review, the current knowledge on HMOs is contextualised to discuss the gaps in scientific understanding and the avenues for future research.
American Psychological Association (APA)
Ray, Chandan& Kerketta, Joshi A.& Rao, Subhash& Patel, Snehal& Dutt, Shantanu& Arora, Kamal…[et al.]. 2019. Human Milk Oligosaccharides: The Journey Ahead. International Journal of Pediatrics،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1167550
Modern Language Association (MLA)
Ray, Chandan…[et al.]. Human Milk Oligosaccharides: The Journey Ahead. International Journal of Pediatrics No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1167550
American Medical Association (AMA)
Ray, Chandan& Kerketta, Joshi A.& Rao, Subhash& Patel, Snehal& Dutt, Shantanu& Arora, Kamal…[et al.]. Human Milk Oligosaccharides: The Journey Ahead. International Journal of Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1167550
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167550