Urinary Tract Infections among HIV-Positive Pregnant Women in Mwanza City, Tanzania, Are High and Predicted by Low CD4+ Count
Joint Authors
Mshana, Stephen E.
Mirambo, Mariam M.
Seni, Jeremiah
Chaula, Tito
Ng’walida, Nhandi
Kajura, Alphaxaid
DeVinney, Rebekah
Source
International Journal of Microbiology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-01-31
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Introduction.
Urinary tract infection (UTI) among pregnant women can lead to adverse maternal and foetal outcomes.
UTI has been widely studied in the general obstetric population in Tanzania; the present study evaluated the magnitude, antimicrobial resistance, and predictors of UTI among HIV-positive pregnant women.
Methods.
Between March and May 2016 midstream urine samples from 234 women attending prevention of mother to child transmission of HIV (PMTCT) clinics were analyzed using standard methods.
Data was analyzed by STATA version 11.0.
Results.
The prevalence of UTI was 21.4%, 50/234 [95% CI: 16.1–26.6].
The asymptomatically significant bacteriuria was higher than symptomatically significant bacteriuria (16.6% versus 4.7%, p<0.001).
On multivariable logistic regression analysis, single marital status (OR: 2.6, 95% CI: 1.1–6.1, and p=0.026), low CD4+ counts of <200/μL (OR: 2.9, 95% CI: 1.1–7.7, and p=0.031), and having UTI symptoms (OR: 2.5, 95% CI: 1.1–6.0, and p=0.03) were independent predictors of UTI.
Escherichia coli predominated (57.7%) and exhibited a low prevalence of resistance to nitrofurantoin (16.7%), gentamicin (10.0%), and ceftriaxone (13.3%).
Four (13.3%) of these were extended-spectrum beta-lactamase producers.
Conclusions.
A considerable proportion of HIV-positive pregnant women in Mwanza have significant bacteriuria which calls for the need to introduce routine UTI screening at PMTCT clinics to guide specific treatment and prevent associated complications.
American Psychological Association (APA)
Chaula, Tito& Seni, Jeremiah& Ng’walida, Nhandi& Kajura, Alphaxaid& Mirambo, Mariam M.& DeVinney, Rebekah…[et al.]. 2017. Urinary Tract Infections among HIV-Positive Pregnant Women in Mwanza City, Tanzania, Are High and Predicted by Low CD4+ Count. International Journal of Microbiology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167570
Modern Language Association (MLA)
Chaula, Tito…[et al.]. Urinary Tract Infections among HIV-Positive Pregnant Women in Mwanza City, Tanzania, Are High and Predicted by Low CD4+ Count. International Journal of Microbiology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1167570
American Medical Association (AMA)
Chaula, Tito& Seni, Jeremiah& Ng’walida, Nhandi& Kajura, Alphaxaid& Mirambo, Mariam M.& DeVinney, Rebekah…[et al.]. Urinary Tract Infections among HIV-Positive Pregnant Women in Mwanza City, Tanzania, Are High and Predicted by Low CD4+ Count. International Journal of Microbiology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167570
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167570