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NT-proBNP, Cardiometabolic Risk Factors, and Nutritional Status in Hemodialysis Patients
Joint Authors
Ducros, Jacques
Larifla, Laurent
Merault, Henri
Foucan, Lydia
Source
International Journal of Nephrology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-09-17
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Background.
We aimed to evaluate the association between NT-proBNP and malnutrition in HD patients while taking into account the four established categories of parameters for diagnosis of protein energy wasting (PEW).
Methods.
A cross-sectional study was performed in Afro-Caribbean dialysis patients.
One component in each of the 4 categories for the wasting syndrome was retained: serum albumin ≤ 38 g/L, BMI ≤ 23 Kg/m2, serum creatinine ≤ 818 µmol/L, and normalized protein catabolic rate (nPCR) ≤ 0.8 g/kg/day.
NT-proBNP was assessed using a chemiluminescence immunoassay.
Two multivariate logistic regression models were performed to determine the parameters associated with high NT-proBNP concentrations.
Results.
In 207 HD patients, 16.9% had PEW (at least three components).
LVEF lower than 60% was found in 13.8% of patients.
NT-proBNP levels ranged from 125 to 33144 pg/mL.
In model 1, high levels of NT-proBNP (≥6243 pg/mL) were independently associated with PEW OR 14.2 (3.25–62.4), male gender 2.80 (1.22–6.57), hsCRP > 5 mg/L 3.90 (1.77–8.57), and dialysis vintage > 3 years 3.84 (1.35–10.8).
In model 2, LVEF OR was 0.93 (0.88–0.98).
NT-proBNP concentrations were significantly higher when the PEW component number was higher.
Conclusion.
In dialysis patients, high NT-proBNP levels must draw attention to cardiac function but also to nutritional status.
American Psychological Association (APA)
Ducros, Jacques& Larifla, Laurent& Merault, Henri& Foucan, Lydia. 2017. NT-proBNP, Cardiometabolic Risk Factors, and Nutritional Status in Hemodialysis Patients. International Journal of Nephrology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167777
Modern Language Association (MLA)
Ducros, Jacques…[et al.]. NT-proBNP, Cardiometabolic Risk Factors, and Nutritional Status in Hemodialysis Patients. International Journal of Nephrology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1167777
American Medical Association (AMA)
Ducros, Jacques& Larifla, Laurent& Merault, Henri& Foucan, Lydia. NT-proBNP, Cardiometabolic Risk Factors, and Nutritional Status in Hemodialysis Patients. International Journal of Nephrology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167777
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167777