Metabolomics Approach for Discrimination and Quality Control of Natural and Commercial Fallopia multiflora Products in Vietnam
Joint Authors
Thoa, Nguyen Thi
Dang, Nguyen Hai
Giang, Do Hoang
Thu Minh, Nguyen Thi
Dat, Nguyen Tien
Source
International Journal of Analytical Chemistry
Issue
Vol. 2020, Issue 2020 (31 Dec. 2020), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2020-11-06
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
A precise HPLC-DAD-based quantification together with the metabolomics statistical method was developed to distinguish and control the quality of Fallopia multiflora, a popular medicinal material in Vietnam.
Multivariate statistical methods such as hierarchical clustering analysis and principal component analysis were utilized to compare and discriminate six natural and twelve commercial samples.
2,3,4′,5-Tetrahydroxystilbene 2-O-β-D-glucopyranoside (THSG) (1), emodin (4), and the new compound 6-hydroxymusizin 8-O-α-D-apiofuranosyl-(1⟶6)-β-D-glucopyranoside (5) could be considered as important markers for classification of F.
multiflora.
Furthermore, seven phenolics were quantified that the variation in the contents of selected metabolites revealed the differences in the quality of natural and commercial samples.
Recovery of the compounds from the analytes was more than 98%, while the limits of detection (LOD) and the limits of quantitation (LOQ) ranged from 0.5 to 6.6 μg/ml and 1.5 to 19.8 μg/ml, respectively.
The linearity, LOD, LOQ, precision, and accuracy satisfied the criteria FDA guidance on bioanalytical methods.
Overall, this method is a promising tool for discrimination and quality assurance of F.
multiflora products.
American Psychological Association (APA)
Thoa, Nguyen Thi& Dang, Nguyen Hai& Giang, Do Hoang& Thu Minh, Nguyen Thi& Dat, Nguyen Tien. 2020. Metabolomics Approach for Discrimination and Quality Control of Natural and Commercial Fallopia multiflora Products in Vietnam. International Journal of Analytical Chemistry،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167781
Modern Language Association (MLA)
Thoa, Nguyen Thi…[et al.]. Metabolomics Approach for Discrimination and Quality Control of Natural and Commercial Fallopia multiflora Products in Vietnam. International Journal of Analytical Chemistry No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1167781
American Medical Association (AMA)
Thoa, Nguyen Thi& Dang, Nguyen Hai& Giang, Do Hoang& Thu Minh, Nguyen Thi& Dat, Nguyen Tien. Metabolomics Approach for Discrimination and Quality Control of Natural and Commercial Fallopia multiflora Products in Vietnam. International Journal of Analytical Chemistry. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1167781
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167781