Factors Predicting Renal Function Outcome after Augmentation Cystoplasty

Joint Authors

Al Taweel, Waleed
Seyam, Raouf
Mehmood, Shahbaz
Firdous, Sadia

Source

International Journal of Nephrology

Issue

Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.

Publisher

Hindawi Publishing Corporation

Publication Date

2017-03-06

Country of Publication

Egypt

No. of Pages

7

Main Subjects

Diseases
Medicine

Abstract EN

We determined the cause of renal deterioration after augmentation cystoplasty (AC).

Twenty-nine adult patients with refractory bladder dysfunction and who underwent ileocystoplasty from 2004 to 2015 were studied.

Patients with a decline in glomerular filtration rate (GFR) after augmentation were reviewed.

The primary outcome was to determine the factors that might lead to deterioration of estimated GFR.

Median follow-up was 7.0±2.6 years.

Significant bladder capacity, end filling pressure, and bladder compliance were achieved from median 114±53.6 to 342.1±68.3 ml (p=.0001), 68.5±19.9 to 28.2±6.9 cm H2O (p=.0001), and 3.0±2.1 to 12.8±3.9 (p=.0001), respectively.

Renal function remained stable and improved in 22 (76%) patients from median eGFR 135±81.98 to 142.82±94.4 ml/min/1.73 m2 (p=.160).

Significant deterioration was found in 7 (24%) patients from median eGFR 68.25±42 to 36.57±35.33 (p=.001).

The causes of renal deterioration were noncompliance to self-catheterization (2 patients), posterior urethral valve/dysplastic kidneys (2 patients), and reflux/infection (2 patients).

On multivariate analysis, recurrent pyelonephritis (OR 3.87, p=0.0155) and noncompliance (OR 30.78, p=0.0156) were significant.

We concluded that AC is not the cause of progression to end-stage renal disease in patients with renal insufficiency.

American Psychological Association (APA)

Mehmood, Shahbaz& Seyam, Raouf& Firdous, Sadia& Al Taweel, Waleed. 2017. Factors Predicting Renal Function Outcome after Augmentation Cystoplasty. International Journal of Nephrology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167819

Modern Language Association (MLA)

Mehmood, Shahbaz…[et al.]. Factors Predicting Renal Function Outcome after Augmentation Cystoplasty. International Journal of Nephrology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1167819

American Medical Association (AMA)

Mehmood, Shahbaz& Seyam, Raouf& Firdous, Sadia& Al Taweel, Waleed. Factors Predicting Renal Function Outcome after Augmentation Cystoplasty. International Journal of Nephrology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167819

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references

Record ID

BIM-1167819