Incidence and Risk Factors for Early Acute Kidney Injury in Nonsurgical Patients: A Cohort Study
Joint Authors
Diaztagle, Juan José
Cely, Javier Enrique
Mendoza, Elkin José
Olivares, Carlos Roberto
Sepúlveda, Oscar Julián
Acosta, Juan Sebastián
Barón, Rafael Andrés
Source
International Journal of Nephrology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-8, 8 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-04-11
Country of Publication
Egypt
No. of Pages
8
Main Subjects
Abstract EN
Introduction.
Detecting acute kidney injury (AKI) in the first days of hospitalization could prevent potentially fatal complications.
However, epidemiological data are scarce, especially on nonsurgical patients.
Objectives.
To determine the incidence and risk factors associated with AKI within five days of hospitalization (EAKI).
Methods.
Prospective cohort of patients hospitalized in the Internal Medicine Department.
Results.
A total of 16% of 400 patients developed EAKI.
The associated risk factors were prehospital treatment with nephrotoxic drugs (2.21 OR; 95% CI 1.12–4.36, p=0.022), chronic kidney disease (CKD) in stages 3 to 5 (3.56 OR; 95% CI 1.55–8.18, p<0.003), and venous thromboembolism (VTE) at admission (5.05 OR; 95% CI 1.59–16.0, p<0.006).
The median length of hospital stay was higher among patients who developed EAKI (8 [IQR 5–14] versus 6 [IQR 4–10], p=0.008) and was associated with an increased requirement for dialysis (4.87 OR 95% CI 2.54 to 8.97, p<0.001) and in-hospital death (3.45 OR; 95% CI 2.18 to 5.48, p<0.001).
Conclusions.
The incidence of EAKI in nonsurgical patients is similar to the worldwide incidence of AKI.
The risk factors included CKD from stage 3 onwards, prehospital treatment with nephrotoxic drugs, and VTE at admission.
EAKI is associated with prolonged hospital stay, increased mortality rate, and dialysis requirement.
American Psychological Association (APA)
Cely, Javier Enrique& Mendoza, Elkin José& Olivares, Carlos Roberto& Sepúlveda, Oscar Julián& Acosta, Juan Sebastián& Barón, Rafael Andrés…[et al.]. 2017. Incidence and Risk Factors for Early Acute Kidney Injury in Nonsurgical Patients: A Cohort Study. International Journal of Nephrology،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167824
Modern Language Association (MLA)
Cely, Javier Enrique…[et al.]. Incidence and Risk Factors for Early Acute Kidney Injury in Nonsurgical Patients: A Cohort Study. International Journal of Nephrology No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1167824
American Medical Association (AMA)
Cely, Javier Enrique& Mendoza, Elkin José& Olivares, Carlos Roberto& Sepúlveda, Oscar Julián& Acosta, Juan Sebastián& Barón, Rafael Andrés…[et al.]. Incidence and Risk Factors for Early Acute Kidney Injury in Nonsurgical Patients: A Cohort Study. International Journal of Nephrology. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1167824
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167824