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Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema
Joint Authors
Bygum, Anette
Rasmussen, Eva Rye
von Buchwald, Christian
Wadelius, Mia
Prasad, Sumangali Chandra
Kamaleswaran, Shailajah
Ajgeiy, Kawa Khaled
Authried, Georg
Pallesen, Kristine Appel U.
Source
International Journal of Otolaryngology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-7, 7 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-02-14
Country of Publication
Egypt
No. of Pages
7
Main Subjects
Abstract EN
Objective.
To asses a cohort of 105 consecutive patients with angiotensin converting enzyme-inhibitor induced angioedema with regard to demographics, risk factors, family history of angioedema, hospitalization, airway management, outcome, and use of diagnostic codes used for the condition.
Study Design.
Cohort study.
Methods.
This was a retrospective cohort study of 105 patients with angiotensin converting enzyme-inhibitor induced angioedema in the period 1995–2014.
Results.
The cohort consisted of 67 females and 38 males (F : M ratio 1.8), with a mean age of 63 [range 26–86] years.
Female gender was associated with a significantly higher risk of angiotensin converting enzyme-inhibitor induced angioedema.
6.7% had a positive family history of angioedema.
Diabetes seemed to be a protective factor with regard to angioedema.
95% experienced angioedema of the head and neck.
4.7% needed intubation or tracheostomy.
74 admissions took place during the study period with a total of 143 days spent in the hospital.
The diagnosis codes most often used for this condition were “DT783 Quincke’s oedema” and “DT78.4 Allergy unspecified”.
Complement C1 inhibitor was normal in all tested patients.
Conclusion.
Female gender predisposes to angiotensin converting enzyme-inhibitor induced angioedema, whereas diabetes seems to be a protective factor.
American Psychological Association (APA)
Rasmussen, Eva Rye& von Buchwald, Christian& Wadelius, Mia& Prasad, Sumangali Chandra& Kamaleswaran, Shailajah& Ajgeiy, Kawa Khaled…[et al.]. 2017. Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema. International Journal of Otolaryngology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167975
Modern Language Association (MLA)
Rasmussen, Eva Rye…[et al.]. Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema. International Journal of Otolaryngology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1167975
American Medical Association (AMA)
Rasmussen, Eva Rye& von Buchwald, Christian& Wadelius, Mia& Prasad, Sumangali Chandra& Kamaleswaran, Shailajah& Ajgeiy, Kawa Khaled…[et al.]. Assessment of 105 Patients with Angiotensin Converting Enzyme-Inhibitor Induced Angioedema. International Journal of Otolaryngology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1167975
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1167975