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Innovative 3D Model of the Human Middle Ear in High Resolution with a Histological Microgrinding Method: A Feasibility Study and Comparison with μCT
Joint Authors
Lenarz, Thomas
Prenzler, Nils Kristian
Bradel, Susanne
Doniga-Crivat, Laura
Besdo, Silke
Lexow, Franziska
Fehr, Michael
Brandes, Gudrun
Source
International Journal of Otolaryngology
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-9, 9 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-05-03
Country of Publication
Egypt
No. of Pages
9
Main Subjects
Abstract EN
Conclusion.
The development of a histological 3D model of the tympanic cavity visualizes the exact microanatomy of the sound conduction organ and is therefore essential for finite elements simulations and surgical training.
Objectives.
So far, no accurate histological 3D model of the sound conduction system existed in literature.
For 3D reconstruction of the very fine structures inside and outside the auditory ossicles, a method based on histological slices allows a more differential analysis of both hard and soft tissues and could thus be superior to μCT.
Method.
A complete temporal bone was embedded in epoxy resin and microground in distances of about 34 μm.
After photodocumentation of every plane, a 3D reconstruction was performed by using the Computer Aided Design (CAD) program Rhinoceros 5®.
For comparison, a μCT of the same specimen resulted in a 3D model of the calcified structures in the middle ear.
Results.
The histological 3D model gives an excellent overview to all anatomical soft and bony tissues of the human auditory ossicles.
Specifically the fine blood vessel system and the exact dimension of cartilage areas inside the ossicles can be illustrated much more precisely than with μCT data.
The present technique also allows the evaluation of the fine connecting ligaments inside the tympanic cavity.
American Psychological Association (APA)
Bradel, Susanne& Doniga-Crivat, Laura& Besdo, Silke& Lexow, Franziska& Fehr, Michael& Lenarz, Thomas…[et al.]. 2017. Innovative 3D Model of the Human Middle Ear in High Resolution with a Histological Microgrinding Method: A Feasibility Study and Comparison with μCT. International Journal of Otolaryngology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1168008
Modern Language Association (MLA)
Bradel, Susanne…[et al.]. Innovative 3D Model of the Human Middle Ear in High Resolution with a Histological Microgrinding Method: A Feasibility Study and Comparison with μCT. International Journal of Otolaryngology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1168008
American Medical Association (AMA)
Bradel, Susanne& Doniga-Crivat, Laura& Besdo, Silke& Lexow, Franziska& Fehr, Michael& Lenarz, Thomas…[et al.]. Innovative 3D Model of the Human Middle Ear in High Resolution with a Histological Microgrinding Method: A Feasibility Study and Comparison with μCT. International Journal of Otolaryngology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1168008
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1168008