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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country
Joint Authors
Gómez-Duarte, Oscar G.
Farfán-García, Ana E.
Zhang, Chengxian
Imdad, Aamer
Arias-Guerrero, Monica Y.
Sánchez-Alvarez, Nayibe T.
Shah, Rikhil
Iqbal, Junaid
Tamborski, Maria E.
Source
International Journal of Pediatrics
Issue
Vol. 2017, Issue 2017 (31 Dec. 2017), pp.1-10, 10 p.
Publisher
Hindawi Publishing Corporation
Publication Date
2017-08-10
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
Introduction.
Acute diarrheal disease (ADD) is a common cause of morbidity and mortality in children under 5 years of age.
Understanding of the etiology of ADD is lacking in most low and middle income countries because reference laboratories detect limited number of pathogens.
The objective of this study was to determine the feasibility to conduct a comprehensive case-control study to survey diarrheal pathogens among children with and without moderate-to-severe ADD.
Materials and Methods.
Microbiology and molecular-based techniques were used to detect viral, bacterial, and parasitic enteropathogens.
The study was conducted in Bucaramanga, Colombia, after Institutional Review Board approval was obtained.
Results.
Ninety children less than 5 years of age were recruited after a written informed consent was obtained from parents or guardians.
Forty-five subjects served as cases with ADD and 45 as controls.
Thirty-six subjects out of 90 (40.0%) were positive for at least one enteropathogen, that is, 20 (44.4%) cases and 16 (35.5%) controls.
Conclusions.
The three most common enteric pathogens were enteroaggregative E.
coli (10.0%), Norovirus (6.7%), and Salmonella spp.
(5.6%).
The E.
coli pathogens were 18.8% of all infections making them the most frequent pathogens.
Half of ADD cases were negative for any pathogens.
American Psychological Association (APA)
Farfán-García, Ana E.& Zhang, Chengxian& Imdad, Aamer& Arias-Guerrero, Monica Y.& Sánchez-Alvarez, Nayibe T.& Shah, Rikhil…[et al.]. 2017. Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country. International Journal of Pediatrics،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1168695
Modern Language Association (MLA)
Farfán-García, Ana E.…[et al.]. Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country. International Journal of Pediatrics No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1168695
American Medical Association (AMA)
Farfán-García, Ana E.& Zhang, Chengxian& Imdad, Aamer& Arias-Guerrero, Monica Y.& Sánchez-Alvarez, Nayibe T.& Shah, Rikhil…[et al.]. Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country. International Journal of Pediatrics. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1168695
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references
Record ID
BIM-1168695